Pub. Date : 1987 Nov
PMID : 3319563
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In rats, type B monoamine oxidase (MAO-B), which mediates the conversion of MPTP to MPP+, may act as an enzymatic barrier at brain microvessels, whereas in primates the enzyme, present mainly in astrocytes, appears important for bioactivation of MPTP into the toxic metabolite. | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | monoamine oxidase B | Rattus norvegicus |
| 2 | In rats, type B monoamine oxidase (MAO-B), which mediates the conversion of MPTP to MPP+, may act as an enzymatic barrier at brain microvessels, whereas in primates the enzyme, present mainly in astrocytes, appears important for bioactivation of MPTP into the toxic metabolite. | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | monoamine oxidase B | Rattus norvegicus |