Title : Dopaminergic toxicity after the stereotaxic administration of the 1-methyl-4-phenylpyridinium ion (MPP+) to rats.

Pub. Date : 1985 Aug 16

PMID : 2413402






3 Functional Relationships(s)
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1 These results are consistent with the premise that MPP+, formed from 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by the enzyme monoamine oxidase B, may be responsible for the toxicity observed after MPTP administration. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine monoamine oxidase B Rattus norvegicus
2 These results are consistent with the premise that MPP+, formed from 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by the enzyme monoamine oxidase B, may be responsible for the toxicity observed after MPTP administration. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine monoamine oxidase B Rattus norvegicus
3 These results are consistent with the premise that MPP+, formed from 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by the enzyme monoamine oxidase B, may be responsible for the toxicity observed after MPTP administration. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine monoamine oxidase B Rattus norvegicus