Pub. Date : 1987
PMID : 3123604
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | MPTP is oxidised to its neurotoxic metabolite, 1-methyl-4-phenylpyridinium (MPP+) by monoamine oxidase B (MAO B). | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | monoamine oxidase B | Rattus norvegicus |
| 2 | MPTP is oxidised to its neurotoxic metabolite, 1-methyl-4-phenylpyridinium (MPP+) by monoamine oxidase B (MAO B). | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | monoamine oxidase B | Rattus norvegicus |
| 3 | MPTP toxicity is prevented by pretreatment with the MAO B inhibitor selegiline ((-)-deprenyl). | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | monoamine oxidase B | Rattus norvegicus |