Quinine

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







17 Article(s)
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1 30945322 Erlotinib treatment induces cytochrome P450 3A activity in non-small cell lung cancer patients. 2019 Aug 1
2 29941014 Inflammation down-regulates CYP3A4-catalysed drug metabolism in hemodialysis patients. 2018 Jun 25 1
3 26693810 In Vivo Cytochrome P450 3A Isoenzyme Activity and Pharmacokinetics of Imatinib in Relation to Therapeutic Outcome in Patients With Chronic Myeloid Leukemia. 2016 Apr 1
4 27366135 Effect of cranberry dietary supplements with different brands on human CYP3A4 enzyme. 2012 2
5 20054526 CYP3A activity influences imatinib response in patients with chronic myeloid leukemia: a pilot study on in vivo CYP3A activity. 2010 Apr 3
6 19353999 Variable inhibitory effect of different brands of commercial herbal supplements on human cytochrome P-450 CYP3A4. 2009 2
7 18300941 4Beta-hydroxycholesterol is a new endogenous CYP3A marker: relationship to CYP3A5 genotype, quinine 3-hydroxylation and sex in Koreans, Swedes and Tanzanians. 2008 Mar 4
8 17200836 Inhibition of CYP3A4 and CYP3A5 catalyzed metabolism of alprazolam and quinine by ketoconazole as racemate and four different enantiomers. 2007 Feb 5
9 15896247 Ketoconazole increases plasma concentrations of antimalarial mefloquine in healthy human volunteers. 2005 Jun 2
10 16171783 Phenotype-genotype variability in the human CYP3A locus as assessed by the probe drug quinine and analyses of variant CYP3A4 alleles. 2005 Dec 9 2
11 12743670 Quinine 3-hydroxylation as a biomarker reaction for the activity of CYP3A4 in man. 2003 May 4
12 12433805 Enzyme kinetics for the formation of 3-hydroxyquinine and three new metabolites of quinine in vitro; 3-hydroxylation by CYP3A4 is indeed the major metabolic pathway. 2002 Dec 3
13 11737987 Inhibition of human CYP3A4 activity by grapefruit flavonoids, furanocoumarins and related compounds. 2001 Sep-Dec 3
14 10456490 Grapefruit juice has no effect on quinine pharmacokinetics. 1999 Jul 1
15 10661723 In vitro hepatic metabolism of a CYP3A-mediated drug, quinine, in Adélie penguins. 1999 Nov 4
16 9088578 Evidence for involvement of human CYP3A in the 3-hydroxylation of quinine. 1997 Mar 5
17 9399990 The In vitro hepatic metabolism of quinine in mice, rats and dogs: comparison with human liver microsomes. 1997 Dec 1