Title : In Vivo Cytochrome P450 3A Isoenzyme Activity and Pharmacokinetics of Imatinib in Relation to Therapeutic Outcome in Patients With Chronic Myeloid Leukemia.

Pub. Date : 2016 Apr

PMID : 26693810






1 Functional Relationships(s)
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1 METHODS: Forty-three patients with CML were phenotyped for CYP3A activity using quinine as a probe drug and evaluated for clinical response parameters. Quinine cytochrome P450 family 3 subfamily A member 4 Homo sapiens