Tacrolimus

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







240 Article(s)
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1 34130909 Ivacaftor-elexacaftor-tezacaftor and tacrolimus combination in cystic fibrosis. 2022 Jan 1
2 34583027 Impact of Pharmacogenetics on Intravenous Tacrolimus Exposure and Conversions to Oral Therapy. 2022 Jan 3
3 34688813 CYP3A7, CYP3A4, and CYP3A5 genetic polymorphisms in recipients rather than donors influence tacrolimus concentrations in the early stages after liver transplantation. 2022 Jan 30 7
4 34781138 Trans-eQTLs of the CYP3A4 and CYP3A5 associated with tacrolimus trough blood concentration in Chinese renal transplant patients. 2022 Jan 2
5 35389944 Composite CYP3A phenotypes influence tacrolimus dose-adjusted concentration in lung transplant recipients. 2022 Jul 1 7
6 35396676 Interactions with the CYP3A inhibitor voriconazole differ between extended-LCP- and immediate-release tacrolimus formulations. 2022 Jun 1
7 35562875 Examination of the Impact of CYP3A4/5 on Drug-Drug Interaction between Schizandrol A/Schizandrol B and Tacrolimus (FK-506): A Physiologically Based Pharmacokinetic Modeling Approach. 2022 Apr 19 3
8 35599203 Paxlovid (Nirmatelvir/Ritonavir) and Tacrolimus Drug-Drug Interaction in a Kidney Transplant Patient with SARS-2-CoV infection: A Case Report. 2022 May 19 1
9 32803289 Diltiazem on tacrolimus exposure and dose sparing in Chinese pediatric primary nephrotic syndrome: impact of CYP3A4, CYP3A5, ABCB1, and SLCO1B3 polymorphisms. 2021 Jan 2
10 32843687 Influence of CYP3A polymorphisms on tacrolimus pharmacokinetics in kidney transplant recipients. 2021 Feb 3
11 32908236 Correction: Influence of CYP3A polymorphisms on tacrolimus pharmacokinetics in kidney transplant recipients. 2021 Feb 1
12 32986876 Clinical significance of personalized tacrolimus dosing by adjusting to donor CYP3A-status in liver transplant recipients. 2021 Apr 6
13 33278239 High Intrapatient Variability in Tacrolimus Exposure Calculated Over a Long Period Is Associated With De Novo Donor-Specific Antibody Development and/or Late Rejection in Thai Kidney Transplant Patients Receiving Concomitant CYP3A4/5 Inhibitors. 2021 Oct 1 1
14 33534527 Unraveling the Genomic Architecture of the CYP3A Locus and ADME Genes for Personalized Tacrolimus Dosing. 2021 Oct 1 1
15 33649515 Functional CYP3A variants affecting tacrolimus trough blood concentrations in Chinese renal transplant recipients. 2021 Jun 2
16 33654003 Unraveling the Genomic Architecture of the CYP3A Locus and ADME Genes for Personalized Tacrolimus Dosing. 2021 Oct 1 2
17 34058078 Association of CYP3A5 polymorphisms and parathyroid hormone with blood level of tacrolimus in patients with end-stage renal disease. 2021 Sep 1
18 34285488 Clinical Evaluation of the Efficacy and Safety of Co-Administration of Wuzhi Capsule and Tacrolimus in Adult Chinese Patients with Myasthenia Gravis. 2021 2
19 34306041 CYP3A422 Genotyping in Clinical Practice: Ready for Implementation? 2021 1
20 34620272 Tacrolimus and herbs interactions: a review. 2021 Oct 1 1
21 34725418 CYP3A-status is associated with blood concentration and dose-requirement of tacrolimus in heart transplant recipients. 2021 Nov 1 6
22 31721244 A novel random forest integrative approach based on endogenous CYP3A4 phenotype for predicting tacrolimus concentrations and dosages in Chinese renal transplant patients. 2020 Apr 6
23 31733802 Successful Treatment of Chronic Myeloid Leukemia With Dasatinib After Kidney Transplantation: A Case Report. 2020 Mar 1
24 31955224 Multiple genetic factors affecting the pharmacokinetic and pharmacodynamic processes of tacrolimus in Chinese myasthenia gravis patients. 2020 May 1
25 32013193 Influence of Germline Genetics on Tacrolimus Pharmacokinetics and Pharmacodynamics in Allogeneic Hematopoietic Stem Cell Transplant Patients. 2020 Jan 29 3
26 32308538 Tacrolimus Concentration after Letermovir Initiation in Hematopoietic Stem Cell Transplantation Recipients Receiving Voriconazole: A Retrospective, Observational Study. 2020 1
27 32690569 Use of phenytoin for treatment of tacrolimus toxicity with superimposed sepsis. 2020 Jul 20 2
28 32712713 Flucloxacillin decreases tacrolimus blood trough levels: a single-center retrospective cohort study. 2020 Dec 1
29 32768638 Co-administration of Wuzhi tablet (Schisandra sphenanthera extract) alters tacrolimus pharmacokinetics in a dose- and time-dependent manner in rats. 2020 Dec 5 2
30 32848756 The Clinical Impact of the C0/D Ratio and the CYP3A5 Genotype on Outcome in Tacrolimus Treated Kidney Transplant Recipients. 2020 3
31 32999170 Effects of Concomitant Administration of Vonoprazan Fumarate on the Tacrolimus Blood Concentration in Kidney Transplant Recipients. 2020 1
32 33312896 Exploring the safety and efficacy of adding ketoconazole to tacrolimus in pediatric renal transplant immunosuppression. 2020 Nov 28 1
33 33350247 [An in vitro study on metabolic interaction between main active components of Salviae Miltiorrhizae Radix et Rhizoma and tacrolimus]. 2020 Nov 2
34 29479631 Clinical aspects of tacrolimus use in paediatric renal transplant recipients. 2019 Jan 3
35 29989304 In vivo CYP3A4 activity does not predict the magnitude of interaction between itraconazole and tacrolimus from an extended release formulation. 2019 Jan 4
36 30058048 Drug-metabolizing enzymes CYP3A as a link between tacrolimus and vitamin D in renal transplant recipients: is it relevant in clinical practice? 2019 Jul 4
37 30295407 Effect of isavuconazole on tacrolimus and sirolimus serum concentrations in allogeneic hematopoietic stem cell transplant patients: A drug-drug interaction study. 2019 Feb 1
38 30489455 Effect of tacrolimus dispositional genetics on acute rejection in the first 2 weeks and estimated glomerular filtration rate in the first 3 months following kidney transplantation. 2019 Jan 2
39 30861159 Incorporation of Gene-Environment Interaction Terms Improved the Predictive Accuracy of Tacrolimus Stable Dose Algorithms in Chinese Adult Renal Transplant Recipients. 2019 Jun 3
40 31045868 Therapeutic Drug Monitoring of Tacrolimus-Personalized Therapy: Second Consensus Report. 2019 Jun 1
41 31061321 Effect of Serum Parathyroid Hormone on Tacrolimus Therapy in Kidney Transplant Patients: A Possible Biomarker for a Tacrolimus Dosage Schedule. 2019 1
42 31152598 Prolonged-Release Tacrolimus Is Less Susceptible to Interaction With the Strong CYP3A Inhibitor Voriconazole in Healthy Volunteers. 2019 Dec 1
43 31190414 Differences in CYP3A genotypes of a liver transplant recipient and the donor liver graft and adjustment of tacrolimus dose. 2019 Aug 3
44 31244435 Association of Genetic Variants in CYP3A4, CYP3A5, CYP2C8, and CYP2C19 with Tacrolimus Pharmacokinetics in Renal Transplant Recipients. 2019 1
45 31261526 Correlation between gene polymorphism and blood concentration of calcineurin inhibitors in renal transplant recipients: An overview of systematic reviews. 2019 Jun 2
46 31401678 CYP3A5 and CYP3A7 genetic polymorphisms affect tacrolimus concentration in pediatric patients with nephrotic range proteinuria. 2019 Nov 1
47 31588879 Impact of CYP3A4/5 and ABCB1 polymorphisms on tacrolimus exposure and response in pediatric primary nephrotic syndrome. 2019 Oct 3
48 31616470 The Impact of CYP3A4*22 on Tacrolimus Pharmacokinetics and Outcome in Clinical Practice at a Single Kidney Transplant Center. 2019 3
49 28945011 Prediction of Drug-Drug Interaction between Tacrolimus and Principal Ingredients of Wuzhi Capsule in Chinese Healthy Volunteers Using Physiologically-Based Pharmacokinetic Modelling. 2018 Mar 1
50 29160300 Genome-wide association study identifies the common variants in CYP3A4 and CYP3A5 responsible for variation in tacrolimus trough concentration in Caucasian kidney transplant recipients. 2018 May 22 3