Title : Multiple genetic factors affecting the pharmacokinetic and pharmacodynamic processes of tacrolimus in Chinese myasthenia gravis patients.

Pub. Date : 2020 May

PMID : 31955224






1 Functional Relationships(s)
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1 RESULTS: In this article, we found multiple SNPs on CYP3A4, CYP3A5, FKBP1A, NFATC2 genes were predicted closely related to tacrolimus serum concentration, therapeutic effect which reflected by QMG score changes or even reasonable drug dose. Tacrolimus cytochrome P450 family 3 subfamily A member 4 Homo sapiens