Title : Examination of the Impact of CYP3A4/5 on Drug-Drug Interaction between Schizandrol A/Schizandrol B and Tacrolimus (FK-506): A Physiologically Based Pharmacokinetic Modeling Approach.

Pub. Date : 2022 Apr 19

PMID : 35562875






3 Functional Relationships(s)
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1 Examination of the Impact of CYP3A4/5 on Drug-Drug Interaction between Schizandrol A/Schizandrol B and Tacrolimus (FK-506): A Physiologically Based Pharmacokinetic Modeling Approach. Tacrolimus cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 Examination of the Impact of CYP3A4/5 on Drug-Drug Interaction between Schizandrol A/Schizandrol B and Tacrolimus (FK-506): A Physiologically Based Pharmacokinetic Modeling Approach. Tacrolimus cytochrome P450 family 3 subfamily A member 4 Homo sapiens
3 Due to their inhibitory effects on cytochrome P450 (CYP) 3A enzymes, SZA/SZB may display drug-drug interaction (DDI) with tacrolimus. Tacrolimus cytochrome P450 family 3 subfamily A member 4 Homo sapiens