Ribavirin

eukaryotic translation initiation factor 4E ; Homo sapiens







43 Article(s)
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1 35339025 Pharmacodynamic and therapeutic pilot studies of single-agent ribavirin in patients with human papillomavirus-related malignancies. 2022 May 6
2 33545678 Preclinical efficacy of ribavirin in SHH and group 3 medulloblastoma. 2021 Feb 5 2
3 33577917 Ribavirin inhibits colorectal cancer growth by downregulating PRMT5 expression and H3R8me2s and H4R3me2s accumulation. 2021 Mar 15 1
4 32606016 Repurposing the FDA-Approved Antiviral Drug Ribavirin as Targeted Therapy for Nasopharyngeal Carcinoma. 2020 Sep 2
5 32736668 Inhibition of eIF4E signaling by ribavirin selectively targets lung cancer and angiogenesis. 2020 Aug 27 3
6 30478448 Targeting EIF4E signaling with ribavirin in infant acute lymphoblastic leukemia. 2019 Mar 16
7 30739792 Targeting eIF4E signaling with ribavirin as a sensitizing strategy for ovarian cancer. 2019 Mar 19 6
8 28573908 The eIF4E inhibitor ribavirin as a potential antilymphoma therapeutic: early clinical data<sup/>. 2018 Jan 1
9 29086249 Inhibition of eIF4E cooperates with chemotherapy and immunotherapy in renal cell carcinoma. 2018 Jun 4
10 29112301 Ribavirin augments doxorubicin's efficacy in human hepatocellular carcinoma through inhibiting doxorubicin-induced eIF4E activation. 2018 Jan 5
11 29487714 Ribavirin as a potential therapeutic for atypical teratoid/rhabdoid tumors. 2018 Jan 30 1
12 29959920 Inhibition of eukaryotic translation initiation factor 4E is effective against chemo-resistance in colon and cervical cancer. 2018 Sep 18 3
13 30174840 Genetic and pharmacological inhibition of eIF4E effectively targets esophageal cancer cells and augments 5-FU's efficacy. 2018 Jul 5
14 30454696 Clinically relevant concentration of anti-viral drug ribavirin selectively targets pediatric osteosarcoma and increases chemosensitivity. 2018 Nov 30 6
15 27932243 Inhibition of mTOR/eIF4E by anti-viral drug ribavirin effectively enhances the effects of paclitaxel in oral tongue squamous cell carcinoma. 2017 Jan 22 12
16 27941882 Use of an anti-viral drug, Ribavirin, as an anti-glioblastoma therapeutic. 2017 May 25 2
17 29049978 Targeting eIF4E inhibits growth, survival and angiogenesis in retinoblastoma and enhances efficacy of chemotherapy. 2017 Dec 5
18 26945967 eIF4E-phosphorylation-mediated Sox2 upregulation promotes pancreatic tumor cell repopulation after irradiation. 2016 May 28 1
19 27114554 Importin 8 mediates m7G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E. 2016 May 10 2
20 27379616 Repositioning of anti-viral drugs as therapy for cervical cancer. 2016 Oct 1
21 27501049 Migration and epithelial-to-mesenchymal transition of lung cancer can be targeted via translation initiation factors eIF4E and eIF4GI. 2016 Sep 2
22 25422161 Multiple myeloma proteostasis can be targeted via translation initiation factor eIF4E. 2015 Feb 5
23 25425688 A phase I trial of ribavirin and low-dose cytarabine for the treatment of relapsed and refractory acute myeloid leukemia with elevated eIF4E. 2015 Jan 1
24 25510279 The eukaryotic translation initiation factor eIF4E in the nucleus: taking the road less traveled. 2015 Jan 1
25 25608710 Genetic and pharmacologic inhibition of eIF4E reduces breast cancer cell migration, invasion, and metastasis. 2015 Mar 15 2
26 25738706 Ribavirin as a tri-targeted antitumor repositioned drug. 2015 May 2
27 26317515 Ribavirin Inhibits the Activity of mTOR/eIF4E, ERK/Mnk1/eIF4E Signaling Pathway and Synergizes with Tyrosine Kinase Inhibitor Imatinib to Impair Bcr-Abl Mediated Proliferation and Apoptosis in Ph+ Leukemia. 2015 6
28 24870236 The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation. 2014 Jul 3 1
29 25477336 When will resistance be futile? 2014 Dec 15 2
30 23471078 Human inducible nitric oxide synthase (iNOS) expression depends on chromosome region maintenance 1 (CRM1)- and eukaryotic translation initiation factor 4E (elF4E)-mediated nucleocytoplasmic mRNA transport. 2013 Apr 1 1
31 23583375 Conformational changes induced in the eukaryotic translation initiation factor eIF4E by a clinically relevant inhibitor, ribavirin triphosphate. 2013 May 10 4
32 21796793 mRNA export and cancer. 2012 Jan-Feb 2
33 22397984 Translation initiation factor eIF4E is a target for tumor cell radiosensitization. 2012 May 1 1
34 21415224 Ribavirin treatment effects on breast cancers overexpressing eIF4E, a biomarker with prognostic specificity for luminal B-type breast cancer. 2011 May 1 4
35 21455212 Inhibition of eIF4E with ribavirin cooperates with common chemotherapies in primary acute myeloid leukemia specimens. 2011 Jul 1
36 22129918 Targeting the oncogene eIF4E in cancer: From the bench to clinical trials. 2011 Dec 1 1
37 20629523 Ribavirin as an anti-cancer therapy: acute myeloid leukemia and beyond? 2010 Oct 3
38 19433856 Molecular targeting of the oncogene eIF4E in acute myeloid leukemia (AML): a proof-of-principle clinical trial with ribavirin. 2009 Jul 9 4
39 20049173 Understanding and Targeting the Eukaryotic Translation Initiation Factor eIF4E in Head and Neck Cancer. 2009 3
40 18706892 Ribavirin targets eIF4E dependent Akt survival signaling. 2008 Oct 24 6
41 16131589 The antiviral drug ribavirin does not mimic the 7-methylguanosine moiety of the mRNA cap structure in vitro. 2005 Oct 3
42 16251386 Further evidence that ribavirin interacts with eIF4E. 2005 Dec 3
43 15601771 Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap. 2004 Dec 28 7