Pub. Date : 2005 Dec
PMID : 16251386
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Further evidence that ribavirin interacts with eIF4E. | Ribavirin | eukaryotic translation initiation factor 4E | Homo sapiens |
| 2 | This commentary discusses the recent reports in RNA by Yan and colleagues and Westman and colleagues of the apparent failure of ribavirin to bind to recombinant eIF4E and inhibit 7-methyl guanosine cap-dependent exogenous mRNA translation of cell extracts in vitro. | Ribavirin | eukaryotic translation initiation factor 4E | Homo sapiens |
| 3 | Possible reasons for the discordant findings of Yan and colleagues and Westman and colleagues are suggested, and direct observation of the specific binding of ribavirin to eIF4E by using mass spectrometry is presented. | Ribavirin | eukaryotic translation initiation factor 4E | Homo sapiens |