Title : Use of an anti-viral drug, Ribavirin, as an anti-glioblastoma therapeutic.

Pub. Date : 2017 May 25

PMID : 27941882






2 Functional Relationships(s)
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1 Ribavirin, the only clinically approved drug known to target eIF4E, is an anti-viral molecule currently used in hepatitis C treatment. Ribavirin eukaryotic translation initiation factor 4E Homo sapiens
2 Our work showed that ribavirin inhibits glioma cell growth and migration, and increases cell cycle arrest and cell death, potentially through modulation of the eIF4E, EZH2 and ERK pathways. Ribavirin eukaryotic translation initiation factor 4E Homo sapiens