| 101 |
29891860 | Microsomal Prostaglandin E Synthase-1 Plays a Critical Role in Long-term Motility Dysfunction after Bowel Obstruction. | 2018 Jun 11 |
3 |
| 102 |
29895492 | Anti-neuroinflammatory effects of Ginkgo biloba extract EGb761 in LPS-activated primary microglial cells. | 2018 May 15 |
1 |
| 103 |
30015253 | Structural insight into the optimization of ethyl 5-hydroxybenzo[g]indol-3-carboxylates and their bioisosteric analogues as 5-LO/m-PGES-1 dual inhibitors able to suppress inflammation. | 2018 Jul 15 |
1 |
| 104 |
30027346 | The renal vasodilatory effect of prostaglandins is ameliorated in isolated-perfused kidneys of endotoxemic mice. | 2018 Nov |
1 |
| 105 |
30053720 | Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammation. | 2018 Aug 5 |
1 |
| 106 |
30205824 | Regulation of calcitonin gene-related peptide expression through the COX-2/mPGES-1/PGE2 pathway in the infrapatellar fat pad in knee osteoarthritis. | 2018 Sep 11 |
1 |
| 107 |
30214544 | Regulation of mPGES-1 composition and cell growth via the MAPK signaling pathway in jurkat cells. | 2018 Oct |
1 |
| 108 |
30312760 | Up-regulation of COX-2 and mPGES-1 by 27-hydroxycholesterol and 4-hydroxynonenal: A crucial role in atherosclerotic plaque instability. | 2018 Dec |
2 |
| 109 |
30333759 | Invalidation of Microsomal Prostaglandin E Synthase-1 (mPGES-1) Reduces Diet-Induced Low-Grade Inflammation and Adiposity. | 2018 |
3 |
| 110 |
30382148 | Augmented liver inflammation in a microsomal prostaglandin E synthase 1 (mPGES-1)-deficient diet-induced mouse NASH model. | 2018 Oct 31 |
2 |
| 111 |
30453998 | Anti-neuroinflammatory effects of GPR55 antagonists in LPS-activated primary microglial cells. | 2018 Nov 19 |
1 |
| 112 |
30463256 | Endothelial Microsomal Prostaglandin E Synthetase-1 Upregulates Vascularity and Endothelial Interleukin-1β in Deteriorative Progression of Experimental Autoimmune Encephalomyelitis. | 2018 Nov 19 |
2 |
| 113 |
30619314 | mPGES-1-Mediated Production of PGE2 and EP4 Receptor Sensing Regulate T Cell Colonic Inflammation. | 2018 |
3 |
| 114 |
27375005 | The involvement of prostaglandin E2 in interleukin-1β evoked anorexia is strain dependent. | 2017 Feb |
4 |
| 115 |
27784694 | Deficiency of mPGES-1 exacerbates renal fibrosis and inflammation in mice with unilateral ureteral obstruction. | 2017 Jan 1 |
3 |
| 116 |
27827823 | G-CSF-induced sympathetic tone provokes fever and primes antimobilizing functions of neutrophils via PGE2. | 2017 Feb 2 |
2 |
| 117 |
28052039 | COX-2/mPGES-1/PGE2 cascade activation mediates uric acid-induced mesangial cell proliferation. | 2017 Feb 7 |
3 |
| 118 |
28086912 | WWL70 attenuates PGE2 production derived from 2-arachidonoylglycerol in microglia by ABHD6-independent mechanism. | 2017 Jan 10 |
2 |
| 119 |
28096371 | COX2/mPGES1/PGE2 pathway regulates PD-L1 expression in tumor-associated macrophages and myeloid-derived suppressor cells. | 2017 Jan 31 |
4 |
| 120 |
28239316 | 15-Hydroxyprostaglandin dehydrogenase as a marker in colon carcinogenesis: analysis of the prostaglandin pathway in human colonic tissue. | 2017 Jan |
1 |
| 121 |
28257996 | Linking of mPGES-1 and iNOS activates stem-like phenotype in EGFR-driven epithelial tumor cells. | 2017 Jun 1 |
1 |
| 122 |
28273917 | Alleviation of Microglial Activation Induced by p38 MAPK/MK2/PGE2 Axis by Capsaicin: Potential Involvement of other than TRPV1 Mechanism/s. | 2017 Mar 8 |
1 |
| 123 |
28341741 | Endogenous prostaglandin E2 amplifies IL-33 production by macrophages through an E prostanoid (EP)2/EP4-cAMP-EPAC-dependent pathway. | 2017 May 19 |
3 |
| 124 |
28458341 | The Role of mPGES-1 in Inflammatory Brain Diseases. | 2017 |
1 |
| 125 |
28487024 | Co-localization of microsomal prostaglandin E synthase-1 with cyclooxygenase-1 in layer II of murine placental syncytiotrophoblasts. | 2017 May |
1 |
| 126 |
28565823 | Corticosterone suppresses IL-1β-induced mPGE2 expression through regulation of the 11β-HSD1 bioactivity of synovial fibroblasts in vitro. | 2017 May |
2 |
| 127 |
28627961 | Microsomal prostaglandin E2 synthase-1 inhibitors: a patent review. | 2017 Sep |
2 |
| 128 |
28628921 | Activation of COX-2/mPGES-1/PGE2 Cascade via NLRP3 Inflammasome Contributes to Albumin-Induced Proximal Tubule Cell Injury. | 2017 |
2 |
| 129 |
28675448 | Inhibition of microsomal PGE synthase-1 reduces human vascular tone by increasing PGI2 : a safer alternative to COX-2 inhibition. | 2017 Nov |
1 |
| 130 |
28854439 | mPGES-1-Derived PGE2 Contributes to Indoxyl Sulfate-Induced Mesangial Cell Proliferation. | 2017 |
7 |
| 131 |
28954232 | Inflammatory Resolution Triggers a Prolonged Phase of Immune Suppression through COX-1/mPGES-1-Derived Prostaglandin E2. | 2017 Sep 26 |
2 |
| 132 |
28979673 | COX-2 mediates PM2.5-induced apoptosis and inflammation in vascular endothelial cells. | 2017 |
3 |
| 133 |
28983247 | Microsomal Prostaglandin E Synthase-1 Expression in Inflammatory Conditions Is Downregulated by Dexamethasone: Seminal Role of the Regulatory Phosphatase MKP-1. | 2017 |
2 |
| 134 |
29042013 | Inhibition of microsomal prostaglandin E-synthase-1 (mPGES-1) selectively suppresses PGE2 in an in vitro equine inflammation model. | 2017 Oct |
6 |
| 135 |
29100270 | Albuminuria confers renal resistance to loop diuretics via the stimulation of NLRP3 inflammasome/prostaglandin signaling in thick ascending limb. | 2017 Sep 29 |
1 |
| 136 |
29100801 | Discovery of furan and dihydrofuran-fused tricyclic benzo[d]imidazole derivatives as potent and orally efficacious microsomal prostaglandin E synthase-1 (mPGES-1) inhibitors: Part-1. | 2017 Dec 1 |
1 |
| 137 |
29226622 | PDE4 inhibitor rolipram inhibits the expression of microsomal prostaglandin E synthase-1 by a mechanism dependent on MAP kinase phosphatase-1. | 2017 Dec |
2 |
| 138 |
29257087 | Microsomal Prostaglandin E Synthase-1 Facilitates an Intercellular Interaction between CD4⁺ T Cells through IL-1β Autocrine Function in Experimental Autoimmune Encephalomyelitis. | 2017 Dec 19 |
2 |
| 139 |
24824420 | COX-2, mPGES-1 and EP2 receptor immunohistochemical expression in canine and feline malignant mammary tumours. | 2016 Sep |
1 |
| 140 |
26543101 | Microsomal Prostaglandin E Synthase-1-Derived PGE2 Inhibits Vascular Smooth Muscle Cell Calcification. | 2016 Jan |
1 |
| 141 |
26585956 | Prostaglandin E synthase is upregulated by Gas6 during cancer-induced venous thrombosis. | 2016 Feb 11 |
2 |
| 142 |
26602278 | Hit-to-lead optimization of phenylsulfonyl hydrazides for a potent suppressor of PGE2 production: Synthesis, biological activity, and molecular docking study. | 2016 Jan 1 |
1 |
| 143 |
26673392 | Identification of novel membrane-associated prostaglandin E synthase-1 (mPGES-1) inhibitors with anti-influenza activities in vitro. | 2016 Jan 22 |
3 |
| 144 |
26739892 | mPGES-1-derived PGE2 contributes to adriamycin-induced podocyte injury. | 2016 Mar 15 |
2 |
| 145 |
26755582 | A dynamic Asp-Arg interaction is essential for catalysis in microsomal prostaglandin E2 synthase. | 2016 Jan 26 |
1 |
| 146 |
26915684 | Structure-Based Design of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors using a Virtual Fragment Growing Optimization Scheme. | 2016 Mar 17 |
2 |
| 147 |
26987561 | Aminothiazoles inhibit RANKL- and LPS-mediated osteoclastogenesis and PGE2 production in RAW 264.7 cells. | 2016 Jun |
2 |
| 148 |
27012893 | Insights into the structure activity relationship of mPGES-1 inhibitors: Hints for better inhibitor design. | 2016 Jul |
1 |
| 149 |
27015117 | PGE2-EP3 signaling pathway contributes to protective effects of misoprostol on cerebral injury in APP/PS1 mice. | 2016 May 3 |
1 |
| 150 |
27059285 | Increased lethality and defective pulmonary clearance of Streptococcus pneumoniae in microsomal prostaglandin E synthase-1-knockout mice. | 2016 Jun 1 |
4 |