Title : mPGES-1-derived PGE2 contributes to adriamycin-induced podocyte injury.

Pub. Date : 2016 Mar 15

PMID : 26739892






2 Functional Relationships(s)
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1 mPGES-1-derived PGE2 contributes to adriamycin-induced podocyte injury. Dinoprostone prostaglandin E synthase Mus musculus
2 More importantly, in mPGES-1-deficient mice, albuminuria induced by ADR showed a remarkable attenuation in line with decreased urinary output of PGE2 and TNF-alpha, highly suggesting an in vivo role of mPGES-1 in mediating podocyte injury. Dinoprostone prostaglandin E synthase Mus musculus