| 1 |
34139918 | Multidimensional mechanisms of metformin in cancer treatment. | 2022 Apr |
3 |
| 2 |
34753372 | Perspectives of metformin use in endometrial cancer and other gynaecological malignancies. | 2022 Apr |
2 |
| 3 |
34879473 | Metformin and its therapeutic applications in autoimmune inflammatory rheumatic disease. | 2022 Jan |
2 |
| 4 |
35007850 | Metformin and MiR-365 synergistically promote the apoptosis of gastric cancer cells via MiR-365-PTEN-AMPK axis. | 2022 Feb |
3 |
| 5 |
35065585 | Radiotherapy and high bilirubin may be metformin like effect on lung cancer via possible AMPK pathway modulation. | 2022 |
2 |
| 6 |
35075807 | Metformin promotes histone deacetylation of optineurin and suppresses tumour growth through autophagy inhibition in ocular melanoma. | 2022 Jan |
2 |
| 7 |
35203528 | Metformin Inhibits ROS Production by Human M2 Macrophages via the Activation of AMPK. | 2022 Jan 29 |
6 |
| 8 |
35241643 | miR-146a impedes the anti-aging effect of AMPK via NAMPT suppression and NAD+/SIRT inactivation. | 2022 Mar 4 |
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| 9 |
35266920 | Metformin Protects Against Sunitinib-induced Cardiotoxicity: Investigating the Role of AMPK. | 2022 Jun 1 |
2 |
| 10 |
35367225 | Metformin to treat Huntington disease: A pleiotropic drug against a multi-system disorder. | 2022 Jun |
1 |
| 11 |
35390687 | Perfluorooctanoic acid alters the developmental trajectory of female germ cells and embryos in rodents and its potential mechanism. | 2022 May 1 |
1 |
| 12 |
35405526 | Metformin alleviates nickel-refining fumes-induced aerobic glycolysis via AMPK/GOLPH3 pathway in vitro and in vivo. | 2022 May 1 |
4 |
| 13 |
35414746 | Single Nucleotide Polymorphism in the 3' Untranslated Region of PRKAA2 on Cardiometabolic Parameters in Type 2 Diabetes Mellitus Patients Who Received Metformin. | 2022 |
1 |
| 14 |
35419709 | The role of AMPK-dependent pathways in cellular and molecular mechanisms of metformin: a new perspective for treatment and prevention of diseases. | 2022 Jun |
7 |
| 15 |
35455439 | A Clinical Perspective of the Multifaceted Mechanism of Metformin in Diabetes, Infections, Cognitive Dysfunction, and Cancer. | 2022 Apr 2 |
1 |
| 16 |
35462933 | PRDM16 Regulating Adipocyte Transformation and Thermogenesis: A Promising Therapeutic Target for Obesity and Diabetes. | 2022 |
1 |
| 17 |
35480097 | Metformin Regulates TET2 Expression to Inhibit Endometrial Carcinoma Proliferation: A New Mechanism. | 2022 |
1 |
| 18 |
35563167 | Targeting Sirt1, AMPK, Nrf2, CK2, and Soluble Guanylate Cyclase with Nutraceuticals: A Practical Strategy for Preserving Bone Mass. | 2022 Apr 26 |
1 |
| 19 |
35588955 | Metformin-ROS-Nrf2 connection in the host defense mechanism against oxidative stress, apoptosis, cancers, and ageing. | 2022 Aug |
2 |
| 20 |
35606343 | Metabolic regulation by the intestinal metformin-AMPK axis. | 2022 May 23 |
1 |
| 21 |
35631452 | Metformin and Cancer, an Ambiguanidous Relationship. | 2022 May 19 |
2 |
| 22 |
32667970 | Metformin directly suppresses atherosclerosis in normoglycaemic mice via haematopoietic adenosine monophosphate-activated protein kinase. | 2021 Apr 23 |
10 |
| 23 |
32737864 | Metformin inhibits pancreatic cancer metastasis caused by SMAD4 deficiency and consequent HNF4G upregulation. | 2021 Feb |
1 |
| 24 |
32897388 | Cellular and Molecular Mechanisms of Metformin Action. | 2021 Jan 28 |
1 |
| 25 |
32994182 | Metformin Mitigates DPP-4 Inhibitor-Induced Breast Cancer Metastasis via Suppression of mTOR Signaling. | 2021 Jan |
1 |
| 26 |
33045408 | Biphasic effect of metformin on human cardiac energetics. | 2021 Mar |
2 |
| 27 |
33236135 | Metformin induces apoptosis and inhibits migration by activating the AMPK/p53 axis and suppressing PI3K/AKT signaling in human cervical cancer cells. | 2021 Jan |
5 |
| 28 |
33365058 | Metformin alleviates β-glycerophosphate-induced calcification of vascular smooth muscle cells via AMPK/mTOR-activated autophagy. | 2021 Jan |
3 |
| 29 |
33510179 | Metformin exerts anti-cancerogenic effects and reverses epithelial-to-mesenchymal transition trait in primary human intrahepatic cholangiocarcinoma cells. | 2021 Jan 28 |
2 |
| 30 |
33513084 | Metformin impairs homing ability and efficacy of mesenchymal stem cells for cardiac repair in streptozotocin-induced diabetic cardiomyopathy in rats. | 2021 Apr 1 |
1 |
| 31 |
33575476 | Metformin enhances anti-cancer effects of cisplatin in meningioma through AMPK-mTOR signaling pathways. | 2021 Mar 26 |
6 |
| 32 |
33609563 | Metformin turns 62 in pharmacotherapy: Emergence of non-glycaemic effects and potential novel therapeutic applications. | 2021 May 5 |
3 |
| 33 |
33625942 | Metformin alleviates cisplatin-induced ototoxicity by autophagy induction possibly via the AMPK/FOXO3a pathway. | 2021 Apr 1 |
5 |
| 34 |
33643408 | Constitutive Androstane Receptor-Mediated Inhibition of Metformin on Phase II Metabolic Enzyme SULT2A1. | 2021 |
2 |
| 35 |
33668426 | Therapeutic Applications of Type 2 Diabetes Mellitus Drug Metformin in Patients with Osteoarthritis. | 2021 Feb 13 |
2 |
| 36 |
33689478 | The intersection of metformin and inflammation. | 2021 May 1 |
1 |
| 37 |
33714781 | Mechanism and application of metformin in kidney diseases: An update. | 2021 Jun |
6 |
| 38 |
33724959 | An AMPK activator as a therapeutic option for congenital nephrogenic diabetes insipidus. | 2021 Apr 22 |
1 |
| 39 |
33747367 | Metformin - its anti-cancer effects in hematologic malignancies. | 2021 Feb 26 |
2 |
| 40 |
33752282 | Hypoxia-Induced Suppression of Antiapoptotic Bcl-2 Expression in Human Bladder Tumor Cells Is Regulated by Caveolin-1-Dependent Adenosine Monophosphate-Activated Protein Kinase Activity. | 2021 Jun |
1 |
| 41 |
33797562 | Metformin: Is It the Well Wisher of Bone Beyond Glycemic Control in Diabetes Mellitus? | 2021 Jun |
1 |
| 42 |
33807522 | Multifaceted Mechanisms of Action of Metformin Which Have Been Unraveled One after Another in the Long History. | 2021 Mar 5 |
4 |
| 43 |
33850553 | Metformin prevents PFKFB3-related aerobic glycolysis from enhancing collagen synthesis in lung fibroblasts by regulating AMPK/mTOR pathway. | 2021 Jun |
6 |
| 44 |
34007848 | Metformin and Fibrosis: A Review of Existing Evidence and Mechanisms. | 2021 |
1 |
| 45 |
34033525 | Metformin: Experimental and Clinical Evidence for a Potential Role in Emphysema Treatment. | 2021 Sep 15 |
1 |
| 46 |
34042039 | Highlighting the Protective or Degenerative Role of AMPK Activators in Dementia Experimental Models. | 2021 |
2 |
| 47 |
34062070 | The role of AMPK/mTOR signaling pathway in anticancer activity of metformin. | 2021 Aug 31 |
1 |
| 48 |
34096218 | Metformin Reduces Vascular Assembly in High Glucose-Treated Human Microvascular Endothelial Cells in An AMPK-Independent Manner. | 2021 Jul |
2 |
| 49 |
34117280 | AMPK activates Parkin independent autophagy and improves post sepsis immune defense against secondary bacterial lung infections. | 2021 Jun 11 |
1 |
| 50 |
34152528 | A Phase I clinical trial of dose-escalated metabolic therapy combined with concomitant radiation therapy in high-grade glioma. | 2021 Jul |
1 |