Title : Metformin - its anti-cancer effects in hematologic malignancies.

Pub. Date : 2021 Feb 26

PMID : 33747367






2 Functional Relationships(s)
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1 The main anti-diabetic effect of metformin mediated through stimulation of adenosine monophosphate (AMP)-activated protein kinase (AMPK) is the inhibition of hepatic gluconeogenesis and triggering glucose uptake in skeletal muscles. Metformin protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
2 Additionally, some new pathways, besides the AMPK activation, were discovered, that can explain wide-range properties of metformin. Metformin protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens