Pub. Date : 2021 Feb 13
PMID : 33668426
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The anti-diabetic effects of metformin are mediated mainly via activation of adenosine monophosphate (AMP)-activated protein kinase (AMPK), which is an energy sensing enzyme activated directly by an increase in the AMP/ATP ratio under conditions of metabolic stress. | Metformin | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
| 2 | We also address the adaptive use of metformin, a known AMPK activator, as a new drug for treatment of patients with OA and T2DM. | Metformin | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |