Metformin

protein kinase AMP-activated catalytic subunit alpha 2 ; Homo sapiens







339 Article(s)
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301 20652679 AMP-activated protein kinase inhibits IL-6-stimulated inflammatory response in human liver cells by suppressing phosphorylation of signal transducer and activator of transcription 3 (STAT3). 2010 Nov 1
302 20966509 [The role of AMP-activated protein kinase in regulation of skeletal muscle metabolism]. 2010 Oct 21 1
303 19153119 The antidiabetic drug metformin: a pharmaceutical AMPK activator to overcome breast cancer resistance to HER2 inhibitors while decreasing risk of cardiomyopathy. 2009 Mar 1
304 19243571 AMP-activated protein kinase and cancer. 2009 May 1
305 19275766 AMP-activated protein kinase pathway: a potential therapeutic target in cardiometabolic disease. 2009 Apr 1
306 19372741 Genome-wide inhibitory impact of the AMPK activator metformin on [kinesins, tubulins, histones, auroras and polo-like kinases] M-phase cell cycle genes in human breast cancer cells. 2009 May 15 3
307 19428322 AMP-activated protein kinase-dependent and -independent mechanisms underlying in vitro antiglioma action of compound C. 2009 Jun 1 2
308 19570618 Activation of AMP-activated kinase as a strategy for managing autosomal dominant polycystic kidney disease. 2009 Dec 1
309 19571378 Regulation of glyceraldehyde 3-phosphate dehydrogenase expression by metformin in HepG2 cells. 2009 Jul 6
310 19579180 Regulation of glucose-6-phosphatase gene expression by insulin and metformin. 2009 Oct 3
311 19644919 Expanding roles for AMP-activated protein kinase in neuronal survival and autophagy. 2009 Sep 1
312 17615555 Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 gene expression by 5-aminoimidazole-4-carboxamide riboside is independent of AMP-activated protein kinase. 2008 Feb 15 1
313 18022388 Role of AMP-activated protein kinase in the metabolic syndrome and in heart disease. 2008 Jan 9 1
314 18076373 AMP activated protein kinase: a next generation target for total metabolic control. 2008 Jan 1
315 18098312 Adenosine monophosphate-activated protein kinase modulates the activated phenotype of hepatic stellate cells. 2008 Feb 1
316 18198220 AMP-activated protein kinase mediates glucocorticoid-induced metabolic changes: a novel mechanism in Cushing's syndrome. 2008 Jun 2
317 18220291 High molecular weight adiponectin inhibits proliferation of hepatic stellate cells via activation of adenosine monophosphate-activated protein kinase. 2008 Feb 1
318 18250273 Phosphorylation of LKB1 at serine 428 by protein kinase C-zeta is required for metformin-enhanced activation of the AMP-activated protein kinase in endothelial cells. 2008 Feb 19 16
319 18334179 [AMPK: a link between metabolism and reproduction?]. 2008 Mar 1
320 18343152 Targeting AMPK: a new therapeutic opportunity in breast cancer. 2008 Jul 1
321 18345405 [Metformin and AMPK: an old drug and a new enzyme in the context of metabolic syndrome]. 2008 Feb 3
322 18405894 Evidence for AMPK-dependent regulation of exocytosis of lipoproteins in a model liver cell line. 2008 Jun 10 2
323 19138981 The effects of adiponectin and metformin on prostate and colon neoplasia involve activation of AMP-activated protein kinase. 2008 Oct 2
324 17095593 Metformin inhibits adenosine 5'-monophosphate-activated kinase activation and prevents increases in neuropeptide Y expression in cultured hypothalamic neurons. 2007 Feb 6
325 17339833 Methyl succinate antagonises biguanide-induced AMPK-activation and death of pancreatic beta-cells through restoration of mitochondrial electron transfer. 2007 Apr 3
326 17496363 The role of AMP kinase in diabetes. 2007 Mar 1
327 18006825 Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells. 2007 Nov 15 7
328 16515522 AMP-activated protein kinase and type 2 diabetes. 2006 1
329 16644802 Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders. 2006 Jul 1 2
330 16868748 Metformin influences cardiomyocyte cell death by pathways that are dependent and independent of caspase-3. 2006 Sep 4
331 17026483 AMP-activated protein kinase: Role in metabolism and therapeutic implications. 2006 Nov 1
332 17065104 5 '-Amino-4-imidazolecarboxamide riboside induces apoptosis in human neuroblastoma cells via the mitochondrial pathway. 2006 4
333 15823720 AMPK activation as a strategy for reversing the endothelial lipotoxicity underlying the increased vascular risk associated with insulin resistance syndrome. 2005 4
334 15899896 Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase. 2005 Jul 1 2
335 15236798 AMPK activation may suppress hepatic production of C-reactive protein by stimulating nitric oxide synthase. 2004 3
336 15371448 AMP-activated protein kinase is required for the lipid-lowering effect of metformin in insulin-resistant human HepG2 cells. 2004 Nov 12 7
337 15732245 [Mitochondrial function--role in insulin resistance and lipid metabolism]. 2004 1
338 12960015 Minireview: the AMP-activated protein kinase cascade: the key sensor of cellular energy status. 2003 Dec 1
339 12145153 The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism. 2002 Aug 7