Triglycerides

peroxisome proliferator activated receptor alpha ; Mus musculus







95 Article(s)
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1 34757855 PPARα/γ, adiponectin, and GLUT4 overexpression induced by moronic acid methyl ester influenced glucose and triglyceride levels of experimental diabetic mice. 2022 Apr 1
2 35290477 The daily caloric restriction and alternate-day fasting ameliorated lipid dysregulation in type 2 diabetic mice by downregulating hepatic pescadillo 1. 2022 Mar 15 2
3 34857752 Dietary excess regulates absorption and surface of gut epithelium through intestinal PPARα. 2021 Dec 2 1
4 34986301 The Effects of PPAR Agonists on Atherosclerosis and Nonalcoholic Fatty Liver Disease in ApoE-/-FXR-/- Mice. 2021 Dec 2
5 32708962 Gemfibrozil Induces Anemia, Leukopenia and Reduces Hematopoietic Stem Cells via PPAR-α in Mice. 2020 Jul 17 1
6 33246954 CRISPR-mediated BMP9 ablation promotes liver steatosis via the down-regulation of PPARα expression. 2020 Nov 1
7 30610082 Hepatic monoacylglycerol acyltransferase 1 is induced by prolonged food deprivation to modulate the hepatic fasting response. 2019 Mar 1
8 30664220 SIRT1 mediates the role of RNA-binding protein QKI 5 in the synthesis of triglycerides in non-alcoholic fatty liver disease mice via the PPARα/FoxO1 signaling pathway. 2019 Mar 2
9 31064103 Fermented Cordyceps militaris Extract Prevents Hepatosteatosis and Adipocyte Hypertrophy in High Fat Diet-Fed Mice. 2019 May 6 1
10 31483154 Loss of hepatic PPARα promotes inflammation and serum hyperlipidemia in diet-induced obesity. 2019 Nov 1 1
11 31581697 Antidiabetic and Antihyperlipidemic Effects of Sulphurenic Acid, a Triterpenoid Compound from Antrodia camphorata, in Streptozotocin-Induced Diabetic Mice. 2019 Oct 2 1
12 31607484 Fenofibrate induces PPARα and BMP2 expression to stimulate osteoblast differentiation. 2019 Dec 3 1
13 31851938 SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα. 2019 Dec 17 1
14 31933883 Abnormality of intestinal cholesterol absorption in ApcMin/+ mice with colon cancer cachexia. 2019 3
15 29141109 Hepatic peroxisome proliferator-activated receptor alpha mediates the major metabolic effects of Wy-14643. 2018 May 1
16 29764990 IRE1α prevents hepatic steatosis by processing and promoting the degradation of select microRNAs. 2018 May 15 1
17 29960113 The olive constituent oleuropein, as a PPARα agonist, markedly reduces serum triglycerides. 2018 Sep 2
18 27624175 A grape seed procyanidin extract inhibits HDAC activity leading to increased Pparα phosphorylation and target-gene expression. 2017 Feb 1
19 27816763 PPARα protects against trans-fatty-acid-containing diet-induced steatohepatitis. 2017 Jan 2
20 28049043 Perfluoroalkyl acids-induced liver steatosis: Effects on genes controlling lipid homeostasis. 2017 Mar 1 2
21 28077274 The role and regulation of the peroxisome proliferator activated receptor alpha in human liver. 2017 May 1
22 28082284 Hepatocyte-specific PPARA expression exclusively promotes agonist-induced cell proliferation without influence from nonparenchymal cells. 2017 Mar 1 1
23 28084058 Selective peroxisome proliferator-activated receptor-α modulator K-877 efficiently activates the peroxisome proliferator-activated receptor-α pathway and improves lipid metabolism in mice. 2017 Jul 1
24 28131861 Alcoholic fatty liver is enhanced in CYP2A5 knockout mice: The role of the PPARα-FGF21 axis. 2017 Mar 15 1
25 27153842 Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice. 2016 Aug 1
26 25108893 Complement activation is involved in the hepatic injury caused by high-dose exposure of mice to perfluorooctanoic acid. 2015 Jun 2
27 25395613 Lipolysis, and not hepatic lipogenesis, is the primary modulator of triglyceride levels in streptozotocin-induced diabetic mice. 2015 Jan 1
28 26875495 Propionate Promotes Fatty Acid Oxidation through the Up-Regulation of Peroxisome Proliferator-Activated Receptor α in Intestinal Epithelial Cells. 2015 2
29 23001493 Hypotriglyceridemic effects of apple polyphenols extract via up-regulation of lipoprotein lipase in triton WR-1339-induced mice. 2014 Jan 1
30 24506873 Circadian clocks and feeding time regulate the oscillations and levels of hepatic triglycerides. 2014 Feb 4 1
31 24865983 Impairments of hepatic gluconeogenesis and ketogenesis in PPARα-deficient neonatal mice. 2014 Jul 15 1
32 24876382 Hypoxia-inducible lipid droplet-associated (HILPDA) is a novel peroxisome proliferator-activated receptor (PPAR) target involved in hepatic triglyceride secretion. 2014 Jul 11 4
33 24899625 Upregulation of hepatic VLDLR via PPARα is required for the triglyceride-lowering effect of fenofibrate. 2014 Aug 1
34 24926685 Peroxisome proliferator-activated receptor α activation induces hepatic steatosis, suggesting an adverse effect. 2014 4
35 25016220 Thyrotropin increases hepatic triglyceride content through upregulation of SREBP-1c activity. 2014 Dec 1
36 25329697 Cardiac-specific ablation of ARNT leads to lipotoxicity and cardiomyopathy. 2014 Nov 1
37 23183531 Mouse KLF11 regulates hepatic lipid metabolism. 2013 Apr 1
38 23220585 Adipose triglyceride lipase is a TG hydrolase of the small intestine and regulates intestinal PPARα signaling. 2013 Feb 2
39 23967086 Role of PPARα and HNF4α in stress-mediated alterations in lipid homeostasis. 2013 1
40 24353834 Effects of d-α-tocopherol supplements on lipid metabolism in a high-fat diet-fed animal model. 2013 Dec 1
41 21499893 Modulation of ammonium perfluorooctanoate-induced hepatic damage by genetically different PPARα in mice. 2012 Jan 1
42 22622461 Reduced kidney lipoprotein lipase and renal tubule triglyceride accumulation in cisplatin-mediated acute kidney injury. 2012 Aug 1 4
43 21354252 Hepatic peroxisome proliferator-activated receptor α may have an important role in the toxic effects of di(2-ethylhexyl)phthalate on offspring of mice. 2011 Oct 28 1
44 21544727 Synergistic improvement in insulin resistance with a combination of fenofibrate and rosiglitazone in obese type 2 diabetic mice. 2011 Apr 2
45 21609322 PPARα-LXR as a novel metabolostatic signalling axis in skeletal muscle that acts to optimize substrate selection in response to nutrient status. 2011 Aug 1 1
46 21750705 VLDL hydrolysis by hepatic lipase regulates PPARδ transcriptional responses. 2011 1
47 21857651 ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1. 2011 Aug 21 1
48 21862726 Farnesol, an isoprenoid, improves metabolic abnormalities in mice via both PPARα-dependent and -independent pathways. 2011 Nov 1
49 20054868 Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity. 2010 Feb 1
50 20065164 Rescue of cardiomyopathy in peroxisome proliferator-activated receptor-alpha transgenic mice by deletion of lipoprotein lipase identifies sources of cardiac lipids and peroxisome proliferator-activated receptor-alpha activators. 2010 Jan 26 1