Title : ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.

Pub. Date : 2011 Aug 21

PMID : 21857651






1 Functional Relationships(s)
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1 Here we show that lipolysis of cellular triglycerides by adipose triglyceride lipase (patatin-like phospholipase domain containing protein 2, encoded by Pnpla2; hereafter referred to as Atgl) generates essential mediator(s) involved in the generation of lipid ligands for PPAR activation. Triglycerides peroxisome proliferator activated receptor alpha Mus musculus