Title : Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity.

Pub. Date : 2010 Feb

PMID : 20054868






1 Functional Relationships(s)
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1 The effect of Kupffer cells on liver triglycerides are at least partially mediated by IL-1beta, which suppresses PPARalpha expression and activity. Triglycerides peroxisome proliferator activated receptor alpha Mus musculus