Title : PPARĪ±-LXR as a novel metabolostatic signalling axis in skeletal muscle that acts to optimize substrate selection in response to nutrient status.

Pub. Date : 2011 Aug 1

PMID : 21609322






1 Functional Relationships(s)
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1 Starvation-induced down-regulation of SCD1 expression was opposed by antecedent LXR activation in wild-type mice, an effect enhanced further by PPARalpha deficiency, which may elicit increased channelling of FA into triacylglycerol to limit lipotoxicity. Triglycerides peroxisome proliferator activated receptor alpha Mus musculus