Title : CRISPR-mediated BMP9 ablation promotes liver steatosis via the down-regulation of PPARĪ± expression.

Pub. Date : 2020 Nov

PMID : 33246954






1 Functional Relationships(s)
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1 In vitro, recombinant BMP9 treatment attenuates triglyceride accumulation by enhancing PPARalpha promoter activity via the activation of p-smad. Triglycerides peroxisome proliferator activated receptor alpha Mus musculus