| 1 |
35286656 | Indomethacin-induced spectral responses of naphthalimide-based dyes to serum albumin: effects of substituent and spacer. | 2022 Apr |
1 |
| 2 |
35344895 | Indomethacin-based near-infrared photosensitizer for targeted photodynamic cancer therapy. | 2022 May |
2 |
| 3 |
33314237 | New indomethacin analogs as selective COX-2 inhibitors: Synthesis, COX-1/2 inhibitory activity, anti-inflammatory, ulcerogenicity, histopathological, and docking studies. | 2021 Apr |
1 |
| 4 |
33586347 | One-Pot Synthesis of Coumarin-Indomethacin Hybrids as COX-2 Targeting Probes for Cancer Imaging. | 2021 May 18 |
1 |
| 5 |
34200764 | Crystallography, Molecular Modeling, and COX-2 Inhibition Studies on Indolizine Derivatives. | 2021 Jun 10 |
1 |
| 6 |
34254099 | Synthesis, characterization, and cellular investigations of porphyrin- and chlorin-indomethacin conjugates for photodynamic therapy of cancer. | 2021 Jul 28 |
2 |
| 7 |
31000626 | Fluorescent indomethacin-dansyl conjugates utilize the membrane-binding domain of cyclooxygenase-2 to block the opening to the active site. | 2019 May 31 |
6 |
| 8 |
31022092 | Effect of Ketoprofen and ATB-352 on the Immature Human Intestine: Identification of Responders and Non-responders. | 2019 May |
2 |
| 9 |
29565462 | Indometacin inhibits the proliferation and activation of human pancreatic stellate cells through the downregulation of COX-2. | 2018 May |
4 |
| 10 |
30067351 | Molecular Dynamics Simulation of Cyclooxygenase-2 Complexes with Indomethacin closo-Carborane Analogs. | 2018 Sep 24 |
1 |
| 11 |
28407689 | Radioiodinated indomethacin amide for molecular imaging of cyclooxygenase-2 expressing tumors. | 2017 Mar 14 |
3 |
| 12 |
28632381 | Molecular Modeling of the Interactions between Carborane-Containing Analogs of Indomethacin and Cyclooxygenase-2. | 2017 Aug 28 |
1 |
| 13 |
29031075 | Discovery of new indomethacin-based analogs with potentially selective cyclooxygenase-2 inhibition and observed diminishing to PGE2 activities. | 2017 Dec 1 |
1 |
| 14 |
29087320 | Coexpression of NOS2 and COX2 accelerates tumor growth and reduces survival in estrogen receptor-negative breast cancer. | 2017 Dec 5 |
1 |
| 15 |
27588346 | Antitumor Activity of Cytotoxic Cyclooxygenase-2 Inhibitors. | 2016 Nov 18 |
4 |
| 16 |
27665290 | Distinct Immunoregulatory Mechanisms in Mesenchymal Stem Cells: Role of the Cytokine Environment. | 2016 Dec |
2 |
| 17 |
25381814 | STIM1 overexpression promotes colorectal cancer progression, cell motility and COX-2 expression. | 2015 Aug 13 |
2 |
| 18 |
25503388 | Glutamate-mediated upregulation of the multidrug resistance protein 2 in porcine and human brain capillaries. | 2015 Feb |
1 |
| 19 |
23852449 | Nonsteroidal anti-inflammatory drugs suppress cancer stem cells via inhibiting PTGS2 (cyclooxygenase 2) and NOTCH/HES1 and activating PPARG in colorectal cancer. | 2014 Feb 1 |
4 |
| 20 |
24460671 | Lead optimization on conventional non-steroidal anti-inflammatory drugs: an approach to reduce gastrointestinal toxicity. | 2014 Jul |
1 |
| 21 |
23678036 | Effects of PGF2α on the expression of uterine activation proteins in pregnant human myometrial cells from upper and lower segment. | 2013 Jul |
1 |
| 22 |
23992308 | Indometacin ameliorates high glucose-induced proliferation and invasion via modulation of e-cadherin in pancreatic cancer cells. | 2013 |
2 |
| 23 |
24003391 | Suppression of Heme Oxygenase-1 by Prostaglandin E2-Protein Kinase A-A-Kinase Anchoring Protein Signaling Is Central for Augmented Cyclooxygenase-2 Expression in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages. | 2013 Sep |
1 |
| 24 |
22577879 | Distinct effects of inflammation on gliosis, osmohomeostasis, and vascular integrity during amyloid beta-induced retinal degeneration. | 2012 Aug |
1 |
| 25 |
20803081 | mTOR signaling is involved in indomethacin and nimesulide suppression of colorectal cancer cell growth via a COX-2 independent pathway. | 2011 Feb |
3 |
| 26 |
20969958 | Effects of esomeprazole on healing of nonsteroidal anti-inflammatory drug (NSAID)-induced gastric ulcers in the presence of a continued NSAID treatment: Characterization of molecular mechanisms. | 2011 Jan |
1 |
| 27 |
21250752 | Atropisomerism observed in indometacin derivatives. | 2011 Feb 18 |
1 |
| 28 |
19830428 | Enhanced 5-fluorouracil cytotoxicity in high cyclooxygenase-2 expressing colorectal cancer cells and xenografts induced by non-steroidal anti-inflammatory drugs via downregulation of dihydropyrimidine dehydrogenase. | 2010 Jul |
1 |
| 29 |
20840837 | Carbon monoxide induces cyclooxygenase-2 expression through MAPKs and PKG in phagocytes. | 2010 Dec |
1 |
| 30 |
21163769 | [Application of non-steroidal anti-inflammatory drugs to enhance 5-fluorouracil efficacy in experimental systems]. | 2010 Dec |
1 |
| 31 |
19048402 | Enhancement of 5-fluorouracil efficacy on high COX-2 expressing HCA-7 cells by low dose indomethacin and NS-398 but not on low COX-2 expressing HT-29 cells. | 2009 Sep |
2 |
| 32 |
19183879 | In vitro anti-inflammatory activity of carvacrol: Inhibitory effect on COX-2 catalyzed prostaglandin E(2) biosynthesis. | 2009 Jan |
1 |
| 33 |
19343061 | Gene expression profiles of human liver cells mediated by hepatitis B virus X protein. | 2009 Apr |
1 |
| 34 |
19661321 | Co-inhibition of cyclooxygenase-2 and dihydropyrimidine dehydrogenase by non-steroidal anti-inflammatory drugs in tumor cells and xenografts. | 2009 Aug |
1 |
| 35 |
17131462 | Design, syntheses, biological evaluation, and docking studies of 2-substituted 5-methylsulfonyl-1-phenyl-1H-indoles: potent and selective in vitro cyclooxygenase-2 inhibitors. | 2007 Jan |
1 |
| 36 |
17994684 | Structure-based design, synthesis, and biological evaluation of indomethacin derivatives as cyclooxygenase-2 inhibiting nitric oxide donors. | 2007 Dec 13 |
4 |
| 37 |
16467309 | Cyclooxygenase-2 induction and prostacyclin release by protease-activated receptors in endothelial cells require cooperation between mitogen-activated protein kinase and NF-kappaB pathways. | 2006 Apr 28 |
1 |
| 38 |
16581252 | Evaluation of glycolamide esters of indomethacin as potential cyclooxygenase-2 (COX-2) inhibitors. | 2006 Jul 15 |
2 |
| 39 |
16775340 | Cyclooxygenase 2 induced by Kaposi's sarcoma-associated herpesvirus early during in vitro infection of target cells plays a role in the maintenance of latent viral gene expression. | 2006 Jul |
1 |
| 40 |
16916844 | Crystal structure of anti-configuration of indomethacin and leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase complex reveals the structural basis of broad spectrum indomethacin efficacy. | 2006 Sep |
1 |
| 41 |
17054584 | Effect of indomethacin on Bfl-1, WISP-1 and proliferating cell nuclear antigen in colon cancer cell line HCT116 cells. | 2006 |
5 |
| 42 |
16048930 | Effect of ciprofloxacin-induced prostaglandin E2 on interleukin-18-treated monocytes. | 2005 Aug |
2 |
| 43 |
16259740 | Development of intestinal, but not gastric damage caused by a low dose of indomethacin in the presence of rofecoxib. | 2005 |
3 |
| 44 |
14706679 | Effects of dexamethasone and sulfasalazine on prostaglandin E2 output by human placental cells in vitro. | 2004 Jan |
1 |
| 45 |
14736730 | Tumor growth inhibition by indomethacin in a mouse model of human medullary thyroid cancer: implication of cyclooxygenases and 15-hydroxyprostaglandin dehydrogenase. | 2004 May |
1 |
| 46 |
15177303 | Is there an inhibitory effect of COX-2 inhibitors on bone healing? | 2004 Aug |
2 |
| 47 |
15464057 | Cyclooxygenase inhibition in human monocytes increases endotoxin-induced TNF alpha without affecting cyclooxygenase-2 expression. | 2004 Oct 6 |
1 |
| 48 |
15546508 | Non-steroidal anti-inflammatory drugs inhibit cellular proliferation and upregulate cyclooxygenase-2 protein expression in endometrial cancer cells. | 2004 Nov |
1 |
| 49 |
12749662 | Successful management of an extreme example of neonatal hyperprostaglandin-E syndrome (Bartter's syndrome) with the new cyclooxygenase-2 inhibitor rofecoxib. | 2003 Apr |
1 |
| 50 |
12870263 | Aspirin and indomethacin exhibit antiproliferative effects and induce apoptosis in T98G human glioblastoma cells. | 2003 Jun |
1 |