Title : Development of intestinal, but not gastric damage caused by a low dose of indomethacin in the presence of rofecoxib.

Pub. Date : 2005

PMID : 16259740






3 Functional Relationships(s)
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1 Indomethacin at 3 mg/kg induced hypermotility and COX-2 expression in the intestine but not in the stomach, both in an atropine-sensitive manner. Indomethacin prostaglandin-endoperoxide synthase 2 Homo sapiens
2 The PG deficiency caused by a low dose of indomethacin produces hypermotility and COX-2 expression in the small intestine, and results in damage when COX-2 is inhibited. Indomethacin prostaglandin-endoperoxide synthase 2 Homo sapiens
3 The PG deficiency caused by a low dose of indomethacin produces hypermotility and COX-2 expression in the small intestine, and results in damage when COX-2 is inhibited. Indomethacin prostaglandin-endoperoxide synthase 2 Homo sapiens