Guanosine Triphosphate

RAN, member RAS oncogene family ; Homo sapiens







184 Article(s)
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51 20609434 Tyr39 of ran preserves the Ran.GTP gradient by inhibiting GTP hydrolysis. 2010 Aug 6 9
52 20951941 A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells. 2010 Oct 19 1
53 19339972 Structural basis for assembly and disassembly of the CRM1 nuclear export complex. 2009 May 1
54 19389996 Crystal structure of the nuclear export receptor CRM1 in complex with Snurportin1 and RanGTP. 2009 May 22 1
55 19536614 Nucleocytoplasmic transport of luciferase gene mRNA requires CRM1/Exportin1 and RanGTPase. 2009 Jun 2
56 19769568 Leishmania donovani Ran-GTPase interacts at the nuclear rim with linker histone H1. 2009 Dec 10 2
57 19805628 Relative contributions of chromatin and kinetochores to mitotic spindle assembly. 2009 Oct 5 1
58 20300488 RanGTPase: A Key Regulator of Nucleocytoplasmic Trafficking. 2009 2
59 18003734 Characterization of the human herpesvirus 6 U69 gene product and identification of its nuclear localization signal. 2008 Jan 1
60 18268099 Importin-beta and the small guanosine triphosphatase Ran mediate chromosome loading of the human chromokinesin Kid. 2008 Feb 11 3
61 18339863 Tumor cell dependence on Ran-GTP-directed mitosis. 2008 Mar 15 1
62 18347012 RanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubules. 2008 May 16 2
63 18420738 Characterization of nuclear import of the domain-specific androgen receptor in association with the importin alpha/beta and Ran-guanosine 5'-triphosphate systems. 2008 Aug 1
64 18469014 The RanGTP gradient - a GPS for the mitotic spindle. 2008 May 15 2
65 18565325 ARA24/Ran enhances the androgen-dependent NH2- and COOH-terminal interaction of the androgen receptor. 2008 Aug 29 2
66 18708071 Kap95p binding induces the switch loops of RanGDP to adopt the GTP-bound conformation: implications for nuclear import complex assembly dynamics. 2008 Nov 21 2
67 18796295 Redox regulation of Ran GTPase. 2008 Nov 21 1
68 17074802 Calcium-dependent regulation of NEMO nuclear export in response to genotoxic stimuli. 2007 Jan 3
69 17359978 Structural and biochemical characterization of the Importin-beta.Ran.GTP.RanBD1 complex. 2007 Apr 3 4
70 17426026 Molecular characterization of the Ran-binding zinc finger domain of Nup153. 2007 Jun 8 1
71 17433702 Biochemical characterization of a family of proteins that stabilizes a plant Ran protein in its GTP-bound conformation. 2007 Jun-Jul 10
72 17483873 Spatial control of mitosis by the GTPase Ran. 2007 Aug 1
73 17703953 Characterization of a ras-related nuclear protein (Ran protein) up-regulated in shrimp antiviral immunity. 2007 Nov 2
74 17878171 The High Mobility Group Box Transcription Factor Nhp6Ap enters the nucleus by a calmodulin-dependent, Ran-independent pathway. 2007 Nov 16 1
75 17916694 Nanomechanical basis of selective gating by the nuclear pore complex. 2007 Oct 26 1
76 16371587 The molecular motor KIFC1 associates with a complex containing nucleoporin NUP62 that is regulated during development and by the small GTPase RAN. 2006 Apr 1
77 16543417 A mitotic lamin B matrix induced by RanGTP required for spindle assembly. 2006 Mar 31 1
78 16627745 Nuclear pores form de novo from both sides of the nuclear envelope. 2006 Apr 21 1
79 16716146 HIV-1 integrase is capable of targeting DNA to the nucleus via an importin alpha/beta-dependent mechanism. 2006 Sep 15 3
80 16930555 Polo-like kinase 1-mediated phosphorylation of the GTP-binding protein Ran is important for bipolar spindle formation. 2006 Oct 13 2
81 15254395 The production and localization of GTP-bound ran in mitotic mammalian tissue culture cells. 2004 Aug 1
82 15351280 Purification of RanGDP, RanGTP, and RanGMPPNP by ion exchange chromatography. 2004 Oct 1 3
83 15356295 Structural requirements for pre-microRNA binding and nuclear export by Exportin 5. 2004 1
84 12773398 Coordinated nuclear export of 60S ribosomal subunits and NMD3 in vertebrates. 2003 Jun 2 2
85 12787777 The small GTPase Ran: interpreting the signs. 2003 Jun 1
86 12840069 Mammalian RanBP1 regulates centrosome cohesion during mitosis. 2003 Aug 15 1
87 14565662 13q deletion in chronic lymphocytic leukemia: characterization of E4.5, a novel chromosome condensation regulator-like guanine nucleotide exchange factor. 2003 Sep 1
88 11911364 Both ran and importins have the ability to function as nuclear mRNA export factors. 2002 Feb 3
89 11932251 Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor. 2002 May 17 3
90 12058015 The mechanism of inhibition of Ran-dependent nuclear transport by cellular ATP depletion. 2002 Jun 10 1
91 12070164 The coiled coil region (amino acids 129-250) of the tumor suppressor protein adenomatous polyposis coli (APC). Its structure and its interaction with chromosome maintenance region 1 (Crm-1). 2002 Aug 30 1
92 12105431 The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly. 2002 Jul 1
93 12121625 Ran binds to chromatin by two distinct mechanisms. 2002 Jul 9 2
94 12194828 Targeting of RCC1 to chromosomes is required for proper mitotic spindle assembly in human cells. 2002 Aug 20 1
95 12417134 Nuclear export of ribosomal subunits. 2002 Nov 1
96 11124902 A role for the basic patch and the C terminus of RanGTP in regulating the dynamic interactions with importin beta, CRM1 and RanBP1. 2001 Jan 12 1
97 11146633 A Ran-independent pathway for export of spliced mRNA. 2001 Jan 1
98 11163242 Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity. 2001 Jan 12 5
99 11231159 Roles of Ran-GTP and Ran-GDP in precursor vesicle recruitment and fusion during nuclear envelope assembly in a human cell-free system. 2001 Feb 6 6
100 11231571 Ran-GTP coordinates regulation of microtubule nucleation and dynamics during mitotic-spindle assembly. 2001 Mar 2