Guanosine Triphosphate

RAN, member RAS oncogene family ; Homo sapiens







184 Article(s)
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1 33186548 Ran-GTP Is Non-essential to Activate NuMA for Mitotic Spindle-Pole Focusing but Dynamically Polarizes HURP Near Chromosomes. 2021 Jan 11 3
2 33912945 On the asymmetric partitioning of nucleocytoplasmic transport - recent insights and open questions. 2021 Apr 1 2
3 32528950 Ran GTPase: A Key Player in Tumor Progression and Metastasis. 2020 1
4 32594833 RanBP1 controls the Ran pathway in mammalian cells through regulation of mitotic RCC1 dynamics. 2020 Aug 10
5 32735816 Mechanochemical Crosstalk Produces Cell-Intrinsic Patterning of the Cortex to Orient the Mitotic Spindle. 2020 Sep 21 1
6 31163384 In Preclinical Model of Ovarian Cancer, the SGK1 Inhibitor SI113 Counteracts the Development of Paclitaxel Resistance and Restores Drug Sensitivity. 2019 Aug 2
7 31484720 REV7 has a dynamic adaptor region to accommodate small GTPase RAN/Shigella IpaB ligands, and its activity is regulated by the RanGTP/GDP switch. 2019 Oct 25 4
8 29040603 Mitosis-specific acetylation tunes Ran effector binding for chromosome segregation. 2018 Feb 1 2
9 29750309 Knockdown of Ran GTPase expression inhibits the proliferation and migration of breast cancer cells. 2018 Jul 1
10 29979793 Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility. 2018 1
11 30237164 OSBP-related protein 4L promotes phospholipase Cβ3 translocation from the nucleus to the plasma membrane in Jurkat T-cells. 2018 Nov 9 2
12 30560466 Anti-Invasive and Anti-Proliferative Effects of shRNA-Loaded Poly(Lactide-Co-Glycolide) Nanoparticles Following RAN Silencing in MDA-MB231 Breast Cancer Cells. 2018 Dec 17 2
13 27852860 Nuclear Export Signal Masking Regulates HIV-1 Rev Trafficking and Viral RNA Nuclear Export. 2017 Feb 1 1
14 28205572 Ran-dependent TPX2 activation promotes acentrosomal microtubule nucleation in neurons. 2017 Feb 13 1
15 28600321 Importin-β and CRM1 control a RANBP2 spatiotemporal switch essential for mitotic kinetochore function. 2017 Aug 1 1
16 28864541 Karyopherins regulate nuclear pore complex barrier and transport function. 2017 Nov 6 1
17 28931593 Active Ran regulates anillin function during cytokinesis. 2017 Nov 15 1
18 26864624 RCC1-dependent activation of Ran accelerates cell cycle and DNA repair, inhibiting DNA damage-induced cell senescence. 2016 Apr 15 5
19 26924245 Up-regulated expression of Ran reveals its potential role to deltamethrin stress in Kc cells. 2016 May 25 1
20 25452301 Disruption of the ran system by cysteine oxidation of the nucleotide exchange factor RCC1. 2015 Feb 1
21 25862163 Purification of nuclear localization signal-containing proteins and its application to investigation of the mechanisms of the cell division cycle. 2015 2
22 25894517 Inter-cellular transport of ran GTPase. 2015 1
23 25981788 The Ran-GTP gradient spatially regulates XCTK2 in the spindle. 2015 Jun 1 5
24 26120835 Formation of a Trimeric Xpo1-Ran[GTP]-Ded1 Exportin Complex Modulates ATPase and Helicase Activities of Ded1. 2015 8
25 26124124 Small GTP-binding protein Ran is regulated by posttranslational lysine acetylation. 2015 Jul 14 5
26 26304119 MYCBP2 Is a Guanosine Exchange Factor for Ran Protein and Determines Its Localization in Neurons of Dorsal Root Ganglia. 2015 Oct 16 1
27 26507377 Lysine-acetylation as a fundamental regulator of Ran function: Implications for signaling of proteins of the Ras-superfamily. 2015 Oct 2 2
28 26625290 Combining dehydration, construct optimization and improved data collection to solve the crystal structure of a CRM1-RanGTP-SPN1-Nup214 quaternary nuclear export complex. 2015 Dec 1
29 26793706 The RanGTP Pathway: From Nucleo-Cytoplasmic Transport to Spindle Assembly and Beyond. 2015 1
30 24563355 Ran GTPase in nuclear envelope formation and cancer metastasis. 2014 1
31 24685647 Comparative proteomic analysis of anti-cancer mechanism by periplocin treatment in lung cancer cells. 2014 2
32 23160023 Downregulation of the small GTPase ras-related nuclear protein accelerates cellular ageing. 2013 Mar 1
33 23536659 Guanine-nucleotide exchange factor RCC1 facilitates a tight binding between the encephalomyocarditis virus leader and cellular Ran GTPase. 2013 Jun 1
34 23878195 Interaction of transportin-SR2 with Ras-related nuclear protein (Ran) GTPase. 2013 Aug 30 1
35 23985042 Molecular connections between nuclear and ciliary import processes. 2013 Aug 28 1
36 24268414 CHD4 is a RanGTP-dependent MAP that stabilizes microtubules and regulates bipolar spindle formation. 2013 Dec 16 2
37 24380075 New mitotic regulators released from chromatin. 2013 Dec 16 2
38 22679017 Characterization of a novel activated Ran GTPase mutant and its ability to induce cellular transformation. 2012 Jul 20 6
39 22773955 The CRM1 nuclear export protein in normal development and disease. 2012 1
40 23028658 Topological and functional properties of the small GTPases protein interaction network. 2012 1
41 25436539 Small GTPase Ran and Ran-binding proteins. 2012 Aug 3
42 21258210 The plant cell nucleus: a true arena for the fight between plants and pathogens. 2011 Jan 1
43 21346411 A precursor microRNA in a cancer cell nucleus: get me out of here! 2011 Mar 15 1
44 21439826 Amphiastral mitotic spindle assembly in vertebrate cells lacking centrosomes. 2011 Apr 12 4
45 21712399 Dynamic mechanisms for pre-miRNA binding and export by Exportin-5. 2011 Aug 2
46 21936775 Kinesin motors and primary cilia. 2011 Oct 3
47 20233715 Inhibition of CRM1-mediated nuclear export of transcription factors by leukemogenic NUP98 fusion proteins. 2010 May 21 1
48 20347844 RCC1 uses a conformationally diverse loop region to interact with the nucleosome: a model for the RCC1-nucleosome complex. 2010 May 14 3
49 20471943 Regulated degradation of spindle assembly factors by the anaphase-promoting complex. 2010 May 14 1
50 20526328 Ciliary entry of the kinesin-2 motor KIF17 is regulated by importin-beta2 and RanGTP. 2010 Jul 2