Title : A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells.

Pub. Date : 2010 Oct 19

PMID : 20951941






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The XPO5 mutant form lacks a C-terminal region that contributes to the formation of the pre-miRNA/XPO5/Ran-GTP ternary complex and pre-miRNAs accumulate in the nucleus. Guanosine Triphosphate RAN, member RAS oncogene family Homo sapiens