Title : Leishmania donovani Ran-GTPase interacts at the nuclear rim with linker histone H1.

Pub. Date : 2009 Dec 10

PMID : 19769568






2 Functional Relationships(s)
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1 Interaction of Ran with core histones H3 and H4, creating in metazoans a chromosomal Ran-GTP gradient important for mitotic spindle assembly, is speculative in Leishmania spp., not only because this parasite undergoes a closed mitosis, but also because the main localization of LdRan is different from that of core histone H3. Guanosine Triphosphate RAN, member RAS oncogene family Homo sapiens
2 Interaction of Ran with core histones H3 and H4, creating in metazoans a chromosomal Ran-GTP gradient important for mitotic spindle assembly, is speculative in Leishmania spp., not only because this parasite undergoes a closed mitosis, but also because the main localization of LdRan is different from that of core histone H3. Guanosine Triphosphate RAN, member RAS oncogene family Homo sapiens