| 1 |
34588632 | Foxo3a tempers excessive glutaminolysis in activated T cells to prevent fatal gut inflammation in the murine IL-10-/- model of colitis. | 2022 Mar |
1 |
| 2 |
35623884 | Lysosomal lipid switch sensitises to nutrient deprivation and mTOR targeting in pancreatic cancer. | 2022 May 27 |
1 |
| 3 |
33653947 | Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1. | 2021 Mar 9 |
1 |
| 4 |
33861966 | The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4. | 2021 Apr 15 |
1 |
| 5 |
34075648 | Glutaminolysis is involved in the activation of mTORC1 in in vitro-produced porcine embryos. | 2021 Jul |
2 |
| 6 |
34096300 | Glutamine Regulates Cell Growth and Casein Synthesis through the CYTHs/ARFGAP1-Arf1-mTORC1 Pathway in Bovine Mammary Epithelial Cells. | 2021 Jun 23 |
4 |
| 7 |
34280391 | PPP1CA/YAP/GS/Gln/mTORC1 pathway activates retinal Müller cells during diabetic retinopathy. | 2021 Sep |
3 |
| 8 |
34376668 | Two parallel pathways connect glutamine metabolism and mTORC1 activity to regulate glutamoptosis. | 2021 Aug 10 |
3 |
| 9 |
34453429 | Disrupting porcine glutaminase does not block preimplantation development and elongation nor decrease mTORC1 activation in conceptuses†. | 2021 Nov 15 |
1 |
| 10 |
34916485 | An RNA-RNA crosstalk network involving HMGB1 and RICTOR facilitates hepatocellular carcinoma tumorigenesis by promoting glutamine metabolism and impedes immunotherapy by PD-L1+ exosomes activity. | 2021 Dec 17 |
1 |
| 11 |
31623699 | Effect of glucose, soya oil and glutamine on protein expression and mammalian target of rapamycin complex 1 pathway of jejunal crypt enterocytes in weaned piglets. | 2020 Mar 14 |
1 |
| 12 |
32019866 | Glutamine and asparagine activate mTORC1 independently of Rag GTPases. | 2020 Mar 6 |
3 |
| 13 |
32709928 | T cell-specific deletion of Pgam1 reveals a critical role for glycolysis in T cell responses. | 2020 Jul 24 |
2 |
| 14 |
30622053 | Efficacy of Dual Inhibition of Glycolysis and Glutaminolysis for Therapy of Renal Lesions in Tsc2+/- Mice. | 2019 Feb |
1 |
| 15 |
30713111 | Inhibiting Glutamine-Dependent mTORC1 Activation Ameliorates Liver Cancers Driven by β-Catenin Mutations. | 2019 May 7 |
1 |
| 16 |
30728400 | The ability to utilise ammonia as nitrogen source is cell type specific and intricately linked to GDH, AMPK and mTORC1. | 2019 Feb 6 |
1 |
| 17 |
30801233 | TEAD1 (TEA Domain Transcription Factor 1) Promotes Smooth Muscle Cell Proliferation Through Upregulating SLC1A5 (Solute Carrier Family 1 Member 5)-Mediated Glutamine Uptake. | 2019 Apr 26 |
1 |
| 18 |
30844724 | Recent advances in understanding of amino acid signaling to mTORC1 activation. | 2019 Mar 1 |
1 |
| 19 |
30865893 | p53 Promotes Cancer Cell Adaptation to Glutamine Deprivation by Upregulating Slc7a3 to Increase Arginine Uptake. | 2019 Mar 12 |
1 |
| 20 |
30899002 | Targeting glutamine-addiction and overcoming CDK4/6 inhibitor resistance in human esophageal squamous cell carcinoma. | 2019 Mar 21 |
1 |
| 21 |
31097446 | Blockage of glutamine-dependent anaplerosis affects mTORC1/2 activity and ultimately leads to cellular senescence-like response. | 2019 May 16 |
2 |
| 22 |
31354497 | Berberine Protects Mice Against Dextran Sulfate Sodium-Induced Colitis by Activating mTORC1 Pathway. | 2019 |
1 |
| 23 |
31428575 | Glutamine Metabolism Drives Growth in Advanced Hormone Receptor Positive Breast Cancer. | 2019 |
1 |
| 24 |
29326164 | The glutamine transporter ASCT2 (SLC1A5) promotes tumor growth independently of the amino acid transporter LAT1 (SLC7A5). | 2018 Feb 23 |
1 |
| 25 |
29466723 | Small-Molecule Screen Identifies De Novo Nucleotide Synthesis as a Vulnerability of Cells Lacking SIRT3. | 2018 Feb 20 |
1 |
| 26 |
29635516 | Metabolomic studies identify changes in transmethylation and polyamine metabolism in a brain-specific mouse model of tuberous sclerosis complex. | 2018 Jun 15 |
1 |
| 27 |
29844341 | Leucine/glutamine and v-ATPase/lysosomal acidification via mTORC1 activation are required for position-dependent regeneration. | 2018 May 29 |
2 |
| 28 |
30194281 | Phospholipase D-dependent mTOR complex 1 (mTORC1) activation by glutamine. | 2018 Oct 19 |
5 |
| 29 |
30242175 | Vps34-mediated macropinocytosis in Tuberous Sclerosis Complex 2-deficient cells supports tumorigenesis. | 2018 Sep 21 |
1 |
| 30 |
28112156 | mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitation. | 2017 Jan 23 |
1 |
| 31 |
28507054 | Glutamine Transporters Are Targets of Multiple Oncogenic Signaling Pathways in Prostate Cancer. | 2017 Aug |
1 |
| 32 |
28628108 | Germline hypomorphic CARD11 mutations in severe atopic disease. | 2017 Aug |
1 |
| 33 |
28723563 | A Positive Feedback Loop between Sestrin2 and mTORC2 Is Required for the Survival of Glutamine-Depleted Lung Cancer Cells. | 2017 Jul 18 |
3 |
| 34 |
28835610 | Glutamine metabolism regulates autophagy-dependent mTORC1 reactivation during amino acid starvation. | 2017 Aug 24 |
12 |
| 35 |
29212209 | Targeted inhibition of glutaminase as a potential new approach for the treatment of NF1 associated soft tissue malignancies. | 2017 Nov 7 |
1 |
| 36 |
29296509 | Amino acid and small GTPase regulation of mTORC1. | 2017 |
2 |
| 37 |
26434594 | PAT4 levels control amino-acid sensitivity of rapamycin-resistant mTORC1 from the Golgi and affect clinical outcome in colorectal cancer. | 2016 Jun 9 |
1 |
| 38 |
26455325 | ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer. | 2016 Jun 16 |
2 |
| 39 |
27070696 | Glycoholics Anonymous: Cancer Sobers Up with mTORC1. | 2016 Apr 11 |
1 |
| 40 |
27690010 | Recent Advances in Understanding Amino Acid Sensing Mechanisms that Regulate mTORC1. | 2016 Sep 29 |
1 |
| 41 |
25298408 | Therapeutic targeting of cellular metabolism in cells with hyperactive mTORC1: a paradigm shift. | 2015 Jan |
1 |
| 42 |
25562323 | Increased glutamine catabolism mediates bone anabolism in response to WNT signaling. | 2015 Feb |
1 |
| 43 |
25567907 | Metabolism. Differential regulation of mTORC1 by leucine and glutamine. | 2015 Jan 9 |
4 |
| 44 |
25587719 | The pathogenic role of persistent milk signaling in mTORC1- and milk-microRNA-driven type 2 diabetes mellitus. | 2015 |
1 |
| 45 |
25613864 | Prolonging the survival of Tsc2 conditional knockout mice by glutamine supplementation. | 2015 Feb 20 |
3 |
| 46 |
25639242 | Nitrogen regulates AMPK to control TORC1 signaling. | 2015 Feb 16 |
1 |
| 47 |
25664849 | Coactivator SRC-2-dependent metabolic reprogramming mediates prostate cancer survival and metastasis. | 2015 Mar 2 |
1 |
| 48 |
25878136 | Intrahippocampal glutamine administration inhibits mTORC1 signaling and impairs long-term memory. | 2015 May |
5 |
| 49 |
25917428 | Glutamine Regulates Cardiac Progenitor Cell Metabolism and Proliferation. | 2015 Aug |
2 |
| 50 |
26203267 | Linking diet to acne metabolomics, inflammation, and comedogenesis: an update. | 2015 |
1 |