Title : Glutamine Regulates Cell Growth and Casein Synthesis through the CYTHs/ARFGAP1-Arf1-mTORC1 Pathway in Bovine Mammary Epithelial Cells.

Pub. Date : 2021 Jun 23

PMID : 34096300






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Glutamine Regulates Cell Growth and Casein Synthesis through the CYTHs/ARFGAP1-Arf1-mTORC1 Pathway in Bovine Mammary Epithelial Cells. Glutamine CREB regulated transcription coactivator 1 Mus musculus
2 Overexpressing or inhibiting the mechanistic target of rapamycin (mTOR) revealed that Gln regulated cell growth and CSN2 synthesis through the mTORC1 pathway. Glutamine CREB regulated transcription coactivator 1 Mus musculus
3 A similar intervention of ADP-ribosylation factor 1 (Arf1) uncovered that Gln activated the mTORC1 pathway through Arf1. Glutamine CREB regulated transcription coactivator 1 Mus musculus
4 Collectively, this study demonstrated that Gln positively regulated cell growth and casein synthesis in BMECs, which works through the CYTHs/ARFGAP1-Arf1-mTORC1 pathway. Glutamine CREB regulated transcription coactivator 1 Mus musculus