Pub. Date : 2015 May
PMID : 25878136
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Intrahippocampal glutamine administration inhibits mTORC1 signaling and impairs long-term memory. | Glutamine | CREB regulated transcription coactivator 1 | Mus musculus |
2 | In vitro studies using serum- and amino acid-starved cells have reported that glutamine addition can either stimulate or repress mTORC1 activity, depending on the particular experimental system that was used. | Glutamine | CREB regulated transcription coactivator 1 | Mus musculus |
3 | We present experimental results indicating that intrahippocampal administration of glutamine to rats reduces mTORC1 activity. | Glutamine | CREB regulated transcription coactivator 1 | Mus musculus |
4 | Taken together, these findings indicate that glutamine can decrease mTORC1 activity in the brain and may have implications for treatments of neurological diseases associated with high mTORC1 signaling. | Glutamine | CREB regulated transcription coactivator 1 | Mus musculus |
5 | Taken together, these findings indicate that glutamine can decrease mTORC1 activity in the brain and may have implications for treatments of neurological diseases associated with high mTORC1 signaling. | Glutamine | CREB regulated transcription coactivator 1 | Mus musculus |