Pub. Date : 2019 May 16
PMID : 31097446
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Blockage of glutamine-dependent anaplerosis affects mTORC1/2 activity and ultimately leads to cellular senescence-like response. | Glutamine | CREB regulated transcription coactivator 1 | Mus musculus |
| 2 | In summary, we disclose that glutamine-dependent anaplerosis is essential to cell growth and closely associated with mTORC1 activation and mTORC2 inactivation, and impedes cellular senescence particularly associated with p16INK4A. | Glutamine | CREB regulated transcription coactivator 1 | Mus musculus |