CPRiL

4 Functional Relationships(s) Download
	Sentence	Compound Name	Protein Name	Organism
1	Celastrol"s miR-223 induction might be due to NF-kappaB inhibition and transient mTOR activation: these two events occurred prior to miR-223 elevation in celastrol-treated cells.	celastrol	mechanistic target of rapamycin kinase	Homo sapiens
2	NF-kappaB inhibitor, like celastrol, could induce miR-223; the induction of miR-223 by NF-kappaB inhibitor or celastrol was reduced by the use of mTOR inhibitor.	celastrol	mechanistic target of rapamycin kinase	Homo sapiens
3	NF-kappaB inhibitor, like celastrol, could induce miR-223; the induction of miR-223 by NF-kappaB inhibitor or celastrol was reduced by the use of mTOR inhibitor.	celastrol	mechanistic target of rapamycin kinase	Homo sapiens
4	Finally and interestingly, miR-223 also could affect NF-kappaB and mTOR and the effects were different between cells treated or not treated with celastrol, thus providing an explanation for differing effects of miR-223 alteration on cellular viability in the presence of celastrol or not.	celastrol	mechanistic target of rapamycin kinase	Homo sapiens