Title : SPAP2, an Ig family receptor containing both ITIMs and ITAMs.

Pub. Date : 2002 May 10

PMID : 12051764






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Tyrosine-phosphorylated SPAP2 is specifically associated with SH2 domain-containing tyrosine kinases Syk and Zap70 and SH2 domain-containing tyrosine phosphatases SHP-1 and SHP-2. Tyrosine protein tyrosine phosphatase non-receptor type 6 Homo sapiens
2 Finally, recruitment of SHP-1 to the tyrosine-phosphorylated ITIMs led to a marked activation of the enzyme. Tyrosine protein tyrosine phosphatase non-receptor type 6 Homo sapiens