Pub. Date : 2000 Aug 25
PMID : 10835420
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A prominent tyrosine-phosphorylated protein of approximately 100 kDa (designated pp100) in epidermal growth factor (EGF)-stimulated A431 cells was found to be a main interaction partner of the protein-tyrosine phosphatase SHP-1 in pull-down experiments with a glutathione S-transferase-SHP-1 fusion protein. | Tyrosine | protein tyrosine phosphatase non-receptor type 6 | Homo sapiens |
| 2 | A prominent tyrosine-phosphorylated protein of approximately 100 kDa (designated pp100) in epidermal growth factor (EGF)-stimulated A431 cells was found to be a main interaction partner of the protein-tyrosine phosphatase SHP-1 in pull-down experiments with a glutathione S-transferase-SHP-1 fusion protein. | Tyrosine | protein tyrosine phosphatase non-receptor type 6 | Homo sapiens |
| 3 | Different p120(ctn) isoforms expressed in human embryonal kidney 293 cells, exhibited differential binding to SHP-1 that correlated partly with the extent of EGF-dependent p120(ctn) tyrosine phosphorylation. | Tyrosine | protein tyrosine phosphatase non-receptor type 6 | Homo sapiens |
| 4 | Functions of p120(ctn), which are regulated by tyrosine phosphorylation, may be modulated by the described SHP-1-p120(ctn) interaction. | Tyrosine | protein tyrosine phosphatase non-receptor type 6 | Homo sapiens |