Title : A new role for platelet-endothelial cell adhesion molecule-1 (CD31): inhibition of TCR-mediated signal transduction.

Pub. Date : 1999 Jul 15

PMID : 10395658






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The PECAM-1 cytoplasmic domain contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) that, when appropriately engaged, becomes phosphorylated on tyrosine residues, creating docking sites for nontransmembrane, Src homology 2 domain-bearing protein tyrosine phosphatase (SHP)-1 and SHP-2. Tyrosine protein tyrosine phosphatase non-receptor type 6 Homo sapiens