Title : Restoration of shp1 expression by 5-AZA-2'-deoxycytidine is associated with downregulation of JAK3/STAT3 signaling in ALK-positive anaplastic large cell lymphoma.

Pub. Date : 2006 Sep

PMID : 16871283






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 SHP1 appears to downregulate JAK3 by two mechanisms: tyrosine dephosphorylation and increased degradation via the proteasome pathway. Tyrosine protein tyrosine phosphatase non-receptor type 6 Homo sapiens