Aspartic Acid

KRAS proto-oncogene, GTPase ; Homo sapiens







52 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 32986951 Mutation-Specific and Common Phosphotyrosine Signatures of KRAS G12D and G13D Alleles. 2021 Jan 1 1
2 34227245 Oncogenic KRAS creates an aspartate metabolism signature in colorectal cancer cells. 2021 Dec 1
3 32335227 Conformational selection in the flaviviral NS2B-NS3 protease. 2020 Jul 1
4 33145412 GTP-State-Selective Cyclic Peptide Ligands of K-Ras(G12D) Block Its Interaction with Raf. 2020 Oct 28 1
5 33230296 KRAS-regulated glutamine metabolism requires UCP2-mediated aspartate transport to support pancreatic cancer growth. 2020 Dec 1
6 29748115 KRAS Activating Signaling Triggers Arteriovenous Malformations. 2018 Jul 1
7 29254168 LC-MS-based metabolomics revealed SLC25A22 as an essential regulator of aspartate-derived amino acids and polyamines in KRAS-mutant colorectal cancer. 2017 Nov 24 2
8 26921316 Aspartate Rescues S-phase Arrest Caused by Suppression of Glutamine Utilization in KRas-driven Cancer Cells. 2016 Apr 22 1
9 27451147 SLC25A22 Promotes Proliferation and Survival of Colorectal Cancer Cells With KRAS Mutations and Xenograft Tumor Progression in Mice via Intracellular Synthesis of Aspartate. 2016 Nov 1
10 27764698 Metabolic Alterations Caused by KRAS Mutations in Colorectal Cancer Contribute to Cell Adaptation to Glutamine Depletion by Upregulation of Asparagine Synthetase. 2016 Nov 3
11 24138715 Across the universe of K-RAS mutations in non-small-cell-lung cancer. 2014 1
12 24852854 KRAS mutations and M2PK upregulation in stool samples from individuals with positive fecal occult blood tests screened for colorectal cancer. 2014 Mar-Apr 1
13 23849768 Distribution of KRAS and BRAF mutations in Moroccan patients with advanced colorectal cancer. 2013 Dec 1
14 24372240 Design, virtual screening and docking study of novel NS3 inhibitors by targeting protein-protein interacting sites of dengue virus - a novel approach. 2013 2
15 22558217 New details of HCV NS3/4A proteinase functionality revealed by a high-throughput cleavage assay. 2012 2
16 23152013 [Predictive biomarkers for anti-EGFR antibodies]. 2012 Nov 2
17 19061898 Binding of a noncovalent inhibitor exploiting the S' region stabilizes the hepatitis C virus NS3 protease conformation in the absence of cofactor. 2009 Jan 30 1
18 19797353 In pancreatic ductal adenocarcinoma blood concentrations of some organochlorine compounds and coffee intake are independently associated with KRAS mutations. 2009 Nov 1
19 18097554 Liver metastasis models of colon cancer for evaluation of drug efficacy using NOD/Shi-scid IL2Rgammanull (NOG) mice. 2008 Jan 1
20 18175625 [The Aragonese mummies of the Basilica of Saint Domenico Maggiore in Naples]. 2006 1
21 15734482 K-ras mutation influences macroscopic features of gastric carcinoma. 2005 Mar 1
22 16060660 Transcription inhibition of oncogenic KRAS by a mutation-selective peptide nucleic acid conjugated to the PKKKRKV nuclear localization signal peptide. 2005 Aug 9 3
23 12947056 ras mutations are associated with aggressive tumor phenotypes and poor prognosis in thyroid cancer. 2003 Sep 1 1
24 10739955 A new approach to gene mutation analysis using "GFP-Display". 2000 Apr 1
25 10915606 NS3 serine protease of bovine viral diarrhea virus: characterization of active site residues, NS4A cofactor domain, and protease-cofactor interactions. 2000 Aug 1 1
26 10344756 Activated Ki-Ras suppresses 12-O-tetradecanoylphorbol-13-acetate-induced activation of the c-Jun NH2-terminal kinase pathway in human colon cancer cells. 1999 May 15 1
27 10463479 H-ras and K-ras gene mutations in primary human soft tissue sarcoma: concomitant mutations of the ras genes. 1999 Aug 1
28 11624203 Renaissance mummies in Italy. 1999 1
29 9645349 Prognostic value of loss of heterozygosity and KRAS2 mutations in lung adenocarcinoma. 1998 Jun 19 1
30 9669809 Proliferative potential and K-ras mutation in epithelial hyperplasia of the gallbladder in patients with anomalous pancreaticobiliary ductal union. 1998 Jul 15 1
31 10022320 Critical genes as early warning signs: example of vinyl chloride. 1998 Dec 28 1
32 9177684 An enzyme-linked immunosorbent assay for detecting proteolytic activity of hepatitis C virus proteinase. 1997 May 1 2
33 9399746 Detection of Ki-ras mutations by PCR and differential hybridization and of p53 mutations by SSCP analysis in endoscopically obtained lavage solution from patients with long-standing ulcerative colitis. 1997 Dec 1
34 8608574 K-ras point mutations in cancerous and noncancerous biliary epithelium in patients with pancreaticobiliary maljunction. 1996 Apr 15 1
35 8641983 Detection of K-ras point mutations at codon 12 in pancreatic juice for the diagnosis of pancreatic cancer by hybridization protection assay: a simple method for the determination of the types of point mutation. 1996 May 2
36 8792713 Detection of K-ras point mutation at codon 12 in pure pancreatic juice collected 3 years and 6 months before the clinical diagnosis of pancreatic cancer. 1996 Sep 1
37 8816895 Primary mediastinal and testicular seminomas: a comparison of K-ras-2 gene sequence and p53 immunoperoxidase analysis of 26 cases. 1996 Sep 1
38 8616107 K-ras genotypes and prognosis in non-small-cell lung cancer. 1995 2
39 7914513 A K-ras 13Gly-->Asp mutation is recognized by HLA-DQ7 restricted T cells in a patient with colorectal cancer. Modifying effect of DQ7 on established cancers harbouring this mutation? 1994 Aug 15 1
40 8060313 A cell-binding Arg-Gly-Asp sequence is present in close proximity to the major linear antigenic region of HCV NS3. 1994 Aug 15 1
41 8091650 Substrate specificity of the NS3 serine proteinase of hepatitis C virus as determined by mutagenesis at the NS3/NS4A junction. 1994 Oct 1
42 8385060 Relationships between c-Ki-ras mutations, HPV types, and prognostic indicators in invasive endocervical adenocarcinomas. 1993 Mar 1
43 8463133 Infrequent ras mutation in human stomach cancers. 1993 Feb 2
44 1327034 The ras gene family in human non-small-cell lung cancer. 1992 1
45 1793483 Activation of Ki-ras gene by point mutation in human liver angiosarcoma associated with vinyl chloride exposure. 1991 1
46 1870574 [Detection of point mutation of Kirsten ras oncogene in pancreatic carcinoma by polymerase chain reaction]. 1991 Apr 1
47 2147282 Evidence that the N-terminal domain of nonstructural protein NS3 from yellow fever virus is a serine protease responsible for site-specific cleavages in the viral polyprotein. 1990 Nov 1
48 2205309 RAS mutations are rare events in Philadelphia chromosome-negative/bcr gene rearrangement-negative chronic myelogenous leukemia, but are prevalent in chronic myelomonocytic leukemia. 1990 Sep 15 1
49 2404571 Glycine to aspartic acid mutations at codon 13 of the c-Ki-ras gene in human gastrointestinal cancers. 1990 Feb 1 2
50 2552437 In vitro tyrosine phosphorylation studies on RAS proteins and calmodulin suggest that polylysine-like basic peptides or domains may be involved in interactions between insulin receptor kinase and its substrate. 1989 Oct 1