Title : LC-MS-based metabolomics revealed SLC25A22 as an essential regulator of aspartate-derived amino acids and polyamines in KRAS-mutant colorectal cancer.

Pub. Date : 2017 Nov 24

PMID : 29254168






2 Functional Relationships(s)
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1 LC-MS-based metabolomics revealed SLC25A22 as an essential regulator of aspartate-derived amino acids and polyamines in KRAS-mutant colorectal cancer. Aspartic Acid KRAS proto-oncogene, GTPase Homo sapiens
2 Collectively, SLC25A22 acts as an essential metabolic regulator during CRC progression as it promotes the synthesis of aspartate-derived amino acids and polyamines in KRAS mutant CRC cells. Aspartic Acid KRAS proto-oncogene, GTPase Homo sapiens