Title : Detection of Ki-ras mutations by PCR and differential hybridization and of p53 mutations by SSCP analysis in endoscopically obtained lavage solution from patients with long-standing ulcerative colitis.

Pub. Date : 1997 Dec

PMID : 9399746






1 Functional Relationships(s)
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1 In two ulcerative colitis patients, a mutation was found in the Ki-ras gene (Gly --> Asp 12 and Gly --> Val 12), and in one patient, a mutation in exon 5 of the p53 gene. Aspartic Acid KRAS proto-oncogene, GTPase Homo sapiens