Title : Binding of a noncovalent inhibitor exploiting the S' region stabilizes the hepatitis C virus NS3 protease conformation in the absence of cofactor.

Pub. Date : 2009 Jan 30

PMID : 19061898






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The inhibitor stabilizes the N-terminal domain of NS3p and the substrate-binding site, and correctly aligns catalytic His-Asp residues. Aspartic Acid KRAS proto-oncogene, GTPase Homo sapiens