Pub. Date : 2020 Oct 28
PMID : 33145412
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A co-crystal structure of peptide KD2 with K-Ras(G12D) GppNHp reveals that this peptide binds in the Switch II groove region with concomitant opening of the Switch II loop and a 40 rotation of the alpha2 helix, and that a threonine residue (Thr10) on KD2 has direct access to the mutant aspartate (Asp12) on K-Ras. | Aspartic Acid | KRAS proto-oncogene, GTPase | Homo sapiens |