| 1 |
35451751 | SH2-Domain Protein Isolation Using Synthetic Phosphorylated Peptides to Study VEGFR2 Signaling. | 2022 |
2 |
| 2 |
32337956 | Insulin receptor substrate 1 overexpression promotes survival of glioblastoma cells through AKT1 activation. | 2020 |
1 |
| 3 |
30923665 | Structural and functional properties of Grb2 SH2 dimer in CD28 binding. | 2019 |
1 |
| 4 |
31184863 | Myristoylation-Dependent Palmitoylation of the Receptor Tyrosine Kinase Adaptor FRS2α. | 2019 Jun 25 |
1 |
| 5 |
31759365 | Repurposing Drugs by In Silico Methods to Target BCR Kinase Domain in Chronic Myeloid Leukemia. | 2019 Nov 1 |
2 |
| 6 |
31844748 | Grb2 dimer interacts with Coumarin through SH2 domains: A combined experimental and molecular modeling study. | 2019 Nov |
1 |
| 7 |
29453318 | Integration of Distinct ShcA Signaling Complexes Promotes Breast Tumor Growth and Tyrosine Kinase Inhibitor Resistance. | 2018 May |
1 |
| 8 |
29523808 | Grb2 and GRAP connect the B cell antigen receptor to Erk MAP kinase activation in human B cells. | 2018 Mar 9 |
2 |
| 9 |
27927989 | Crystal Structures and Thermodynamic Analysis Reveal Distinct Mechanisms of CD28 Phosphopeptide Binding to the Src Homology 2 (SH2) Domains of Three Adaptor Proteins. | 2017 Jan 20 |
1 |
| 10 |
28690151 | Identification of STS-1 as a novel ShcA-binding protein. | 2017 Sep 2 |
1 |
| 11 |
28951535 | Dimerization of the adaptor Gads facilitates antigen receptor signaling by promoting the cooperative binding of Gads to the adaptor LAT. | 2017 Sep 26 |
2 |
| 12 |
29182244 | Allosteric Modulation of Grb2 Recruitment to the Intrinsically Disordered Scaffold Protein, LAT, by Remote Site Phosphorylation. | 2017 Dec 13 |
2 |
| 13 |
27543756 | Role of Herpes simplex virus 1 VP11/12 tyrosine-based binding motifs for Src family kinases, p85, Grb2 and Shc in activation of the phosphoinositide 3-kinase-Akt pathway. | 2016 Nov |
2 |
| 14 |
25391654 | Conformational dynamics of the focal adhesion targeting domain control specific functions of focal adhesion kinase in cells. | 2015 Jan 2 |
1 |
| 15 |
25535246 | A THEMIS:SHP1 complex promotes T-cell survival. | 2015 Feb 3 |
1 |
| 16 |
25961473 | Conformation-Dependent Human p52Shc Phosphorylation by Human c-Src. | 2015 Jun 9 |
1 |
| 17 |
26103942 | Grb2 monomer-dimer equilibrium determines normal versus oncogenic function. | 2015 Jun 24 |
1 |
| 18 |
26552706 | DNAM-1 controls NK cell activation via an ITT-like motif. | 2015 Nov 16 |
1 |
| 19 |
24248601 | Grb2 promotes integrin-induced focal adhesion kinase (FAK) autophosphorylation and directs the phosphorylation of protein tyrosine phosphatase α by the Src-FAK kinase complex. | 2014 Feb |
1 |
| 20 |
24265393 | Growth factor receptor-bound protein 2 contributes to (hem)immunoreceptor tyrosine-based activation motif-mediated signaling in platelets. | 2014 Jan 31 |
4 |
| 21 |
25413232 | The immunoglobulin tail tyrosine motif upgrades memory-type BCRs by incorporating a Grb2-Btk signalling module. | 2014 Nov 21 |
1 |
| 22 |
23027125 | HER2 stabilizes EGFR and itself by altering autophosphorylation patterns in a manner that overcomes regulatory mechanisms and promotes proliferative and transformation signaling. | 2013 Aug 29 |
1 |
| 23 |
23277357 | Distinct phosphotyrosine-dependent functions of the ShcA adaptor protein are required for transforming growth factor β (TGFβ)-induced breast cancer cell migration, invasion, and metastasis. | 2013 Feb 15 |
1 |
| 24 |
23826330 | A Novel Phosphopeptide Microarray Based Interactome Map in Breast Cancer Cells Reveals Phosphoprotein-GRB2 Cell Signaling Networks. | 2013 |
1 |
| 25 |
23946459 | Role of herpes simplex virus VP11/12 tyrosine-based motifs in binding and activation of the Src family kinase Lck and recruitment of p85, Grb2, and Shc. | 2013 Oct |
2 |
| 26 |
24003223 | A brain-specific Grb2-associated regulator of extracellular signal-regulated kinase (Erk)/mitogen-activated protein kinase (MAPK) (GAREM) subtype, GAREM2, contributes to neurite outgrowth of neuroblastoma cells by regulating Erk signaling. | 2013 Oct 11 |
5 |
| 27 |
22327338 | c-ABL modulates MAP kinases activation downstream of VEGFR-2 signaling by direct phosphorylation of the adaptor proteins GRB2 and NCK1. | 2012 Jun |
4 |
| 28 |
22505611 | Grb2 mediates semaphorin-4D-dependent RhoA inactivation. | 2012 Aug 1 |
2 |
| 29 |
22521882 | Global tyrosine kinome profiling of human thyroid tumors identifies Src as a promising target for invasive cancers. | 2012 May 11 |
1 |
| 30 |
22683472 | Effect of EGF-receptor tyrosine kinase inhibitor on Rab5 function during endocytosis. | 2012 Sep 1 |
1 |
| 31 |
22726438 | Inhibition of basal FGF receptor signaling by dimeric Grb2. | 2012 Jun 22 |
1 |
| 32 |
22828513 | Biophysical studies with AICD-47 reveal unique binding behavior characteristic of an unfolded domain. | 2012 Aug 24 |
1 |
| 33 |
23150065 | A high-content imaging workflow to study Grb2 signaling complexes by expression cloning. | 2012 Oct 30 |
1 |
| 34 |
20933011 | FCRL6 receptor: expression and associated proteins. | 2011 Jan 30 |
1 |
| 35 |
21625213 | HPV16 E5 affects the KGFR/FGFR2b-mediated epithelial growth through alteration of the receptor expression, signaling and endocytic traffic. | 2011 Dec 15 |
1 |
| 36 |
21784853 | Distinct involvement of the Gab1 and Grb2 adaptor proteins in signal transduction by the related receptor tyrosine kinases RON and MET. | 2011 Sep 16 |
1 |
| 37 |
22001015 | Functional implications of the conformational switch in AICD peptide upon binding to Grb2-SH2 domain. | 2011 Nov 25 |
1 |
| 38 |
22027826 | ACAP4 protein cooperates with Grb2 protein to orchestrate epidermal growth factor-stimulated integrin β1 recycling in cell migration. | 2011 Dec 23 |
1 |
| 39 |
19508206 | Effects of peptidic antagonists of Grb2-SH2 on human breast cancer cells. | 2010 Jan |
1 |
| 40 |
19735729 | Direct binding of Grb2 SH3 domain to FGFR2 regulates SHP2 function. | 2010 Jan |
1 |
| 41 |
20398064 | Tyrosine phosphorylation of R3 subtype receptor-type protein tyrosine phosphatases and their complex formations with Grb2 or Fyn. | 2010 May |
4 |
| 42 |
20554525 | Involvement of Grb2 adaptor protein in nucleophosmin-anaplastic lymphoma kinase (NPM-ALK)-mediated signaling and anaplastic large cell lymphoma growth. | 2010 Aug 20 |
4 |
| 43 |
20623096 | New concepts in phospholipase D signaling in inflammation and cancer. | 2010 Jul 7 |
1 |
| 44 |
20644716 | Themis2/ICB1 is a signaling scaffold that selectively regulates macrophage Toll-like receptor signaling and cytokine production. | 2010 Jul 13 |
1 |
| 45 |
19233262 | Non-redundant roles of the Gab1 and Gab2 scaffolding adapters in VEGF-mediated signalling, migration, and survival of endothelial cells. | 2009 Jun |
1 |
| 46 |
19273609 | Tyrosine phosphorylation of Grb2: role in prolactin/epidermal growth factor cross talk in mammary epithelial cell growth and differentiation. | 2009 May |
4 |
| 47 |
19289054 | Molecular dynamics simulations reveal that Tyr-317 phosphorylation reduces Shc binding affinity for phosphotyrosyl residues of epidermal growth factor receptor. | 2009 Mar 18 |
1 |
| 48 |
19419970 | Prolectin, a glycan-binding receptor on dividing B cells in germinal centers. | 2009 Jul 3 |
1 |
| 49 |
19427038 | PI3 kinase function is vital for the function but not formation of LAT-mediated signaling complexes. | 2009 Jul |
1 |
| 50 |
19509291 | GAREM, a novel adaptor protein for growth factor receptor-bound protein 2, contributes to cellular transformation through the activation of extracellular signal-regulated kinase signaling. | 2009 Jul 24 |
1 |