Title : Conformational dynamics of the focal adhesion targeting domain control specific functions of focal adhesion kinase in cells.

Pub. Date : 2015 Jan 2

PMID : 25391654






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Phosphorylation of FAT on Tyr(925) facilitates FA disassembly and connects to the MAPK pathway through Grb2 association, but requires dissociation of the first helix (H1) of the four-helix bundle of FAT. Tyrosine growth factor receptor bound protein 2 Homo sapiens