Pub. Date : 2019 Nov 1
PMID : 31759365
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Our aim is to explore regions outside the BCR-ABL oncoprotein to identify potential therapeutic targets to curb drug resistance by targeting growth factor receptor-bound protein-2 (Grb-2) which binds to BCR-ABL at the phosphorylated tyrosine (Y177) thereby activating the Ras and PI3K/AKT signaling pathway. | Tyrosine | growth factor receptor bound protein 2 | Homo sapiens |
2 | Our aim is to explore regions outside the BCR-ABL oncoprotein to identify potential therapeutic targets to curb drug resistance by targeting growth factor receptor-bound protein-2 (Grb-2) which binds to BCR-ABL at the phosphorylated tyrosine (Y177) thereby activating the Ras and PI3K/AKT signaling pathway. | Tyrosine | growth factor receptor bound protein 2 | Homo sapiens |