solute carrier family 3 member 2 ; Homo sapiens






171 Article(s)
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51 15151999 Membrane topology of system xc- light subunit reveals a re-entrant loop with substrate-restricted accessibility. J Biol Chem 2004 Jul 23 3
52 15757906 Identification and functional characterization of a novel low affinity aromatic-preferring amino acid transporter (arpAT). One of the few proteins silenced during primate evolution. J Biol Chem 2005 May 13 2
53 15769744 Identification of stereoselective transporters for S-nitroso-L-cysteine: role of LAT1 and LAT2 in biological activity of S-nitrosothiols. J Biol Chem 2005 May 20 1
54 15880135 Activation of epithelial CD98 glycoprotein perpetuates colonic inflammation. Lab Invest 2005 Jul 2
55 16014042 Cystine and glutamate transport in renal epithelial cells transfected with human system x(-) (c). Kidney Int 2005 Aug 3
56 16046863 Manipulation of the phenylalanine metabolism in human keratinocytes by retroviral mediated gene transfer. Cells Tissues Organs 2005 1
57 16103098 Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance. Cancer Res 2005 Aug 15 4
58 16125134 Site-directed mutagenesis of cysteine residues of large neutral amino acid transporter LAT1. Biochim Biophys Acta 2005 Sep 15 5
59 16176881 Inter-individual variation in brain phenylalanine concentration in patients with PKU is not caused by genetic variation in the 4F2hc/LAT1 complex. Mol Genet Metab 2005 Dec 2
60 16399997 Distribution of the cystine/glutamate antiporter system xc- in the brain, kidney, and duodenum. J Histochem Cytochem 2006 May 1
61 16415532 Localization of rat cytochrome P450 in various tissues and comparison of arachidonic acid metabolism by rat P450 with that by human P450 orthologs. Drug Metab Pharmacokinet 2005 Dec 1
62 17023546 Characterization of the human intestinal CD98 promoter and its regulation by interferon-gamma. Am J Physiol Gastrointest Liver Physiol 2007 Feb 1
63 17329830 L-type amino acid transporter-1 expressed in human astrocytomas, U343MGa. Biol Pharm Bull 2007 Mar 1
64 17367118 Chemoinformatics analysis identifies cytotoxic compounds susceptible to chemoresistance mediated by glutathione and cystine/glutamate transport system xc-. J Med Chem 2007 Apr 19 2
65 17451431 Membrane trafficking of CD98 and its ligand galectin 3 in BeWo cells--implication for placental cell fusion. FEBS J 2007 Jun 4
66 17611393 Bridge linkage role played by CD98hc of anti-tumor drug resistance and cancer metastasis on cisplatin-resistant ovarian cancer cells. Cancer Biol Ther 2007 Jun 4
67 17724034 The structure of human 4F2hc ectodomain provides a model for homodimerization and electrostatic interaction with plasma membrane. J Biol Chem 2007 Oct 26 5
68 17764084 Lysinuric protein intolerance: update and extended mutation analysis of the SLC7A7 gene. Hum Mutat 2008 Jan 1
69 18379071 Chloroquine, an anti-malarial agent, acts as a novel regulator of beta 1-integrin-mediated cell-cell adhesion. Biol Pharm Bull 2008 Apr 5
70 18587263 CD98 activation increases surface expression and clusteringof beta1 integrins in MCF-7 cells through FAK/Src- and cytoskeleton-independent mechanisms. Exp Mol Med 2008 Jun 30 6
71 18660501 Identification and characterization of a diamine exporter in colon epithelial cells. J Biol Chem 2008 Sep 26 5
72 18829766 Kaposi's sarcoma-associated herpesvirus forms a multimolecular complex of integrins (alphaVbeta5, alphaVbeta3, and alpha3beta1) and CD98-xCT during infection of human dermal microvascular endothelial cells, and CD98-xCT is essential for the postentry stage of infection. J Virol 2008 Dec 1
73 18992769 Nutrient transporters in cancer: relevance to Warburg hypothesis and beyond. Pharmacol Ther 2009 Jan 1
74 19065266 Ecto-phosphorylation of CD98 regulates cell-cell interactions. PLoS One 2008 5
75 19118595 Gene expression signatures in peripheral blood cells from Japanese women exposed to environmental cadmium. Toxicology 2009 Mar 4 1
76 19182504 Induction of upregulation and downregulation of the T-cell activation marker CD98 in patients undergoing contrast-enhanced CT with iodinated non-ionic dimeric contrast medium. Korean J Radiol 2009 Jan-Feb 1
77 19302270 Discovery of new cargo proteins that enter cells through clathrin-independent endocytosis. Traffic 2009 May 1
78 19433864 Targeted glycoproteomic identification of cancer cell glycosylation. Glycobiology 2009 Aug 1
79 19576658 Cell-permeable ceramides act as novel regulators of U937 cell-cell adhesion mediated by CD29, CD98, and CD147. Immunobiology 2010 Apr 5
80 19808856 Progesterone and mifepristone regulate L-type amino acid transporter 2 and 4F2 heavy chain expression in uterine leiomyoma cells. J Clin Endocrinol Metab 2009 Nov 6
81 19895572 Conventional protein kinase C plays a critical role in negative regulation of CD98-induced homotypic aggregation. Tissue Antigens 2010 Jan 6
82 20045933 Matrine induces cell anergy in human Jurkat T cells through modulation of mitogen-activated protein kinases and nuclear factor of activated T-cells signaling with concomitant up-regulation of anergy-associated genes expression. Biol Pharm Bull 2010 2
83 20053169 Mechanisms of oxidative glutamate toxicity: the glutamate/cystine antiporter system xc- as a neuroprotective drug target. CNS Neurol Disord Drug Targets 2010 Jul 1
84 20375792 Properties of L-type amino acid transporter 1 in epidermal ovarian cancer. Int J Gynecol Cancer 2010 Apr 1
85 20976164 Human endometrial CD98 is essential for blastocyst adhesion. PLoS One 2010 Oct 15 1
86 21150635 Peripheral and central augmentation indexes in relation to the CYP4F2 polymorphisms in Chinese. J Hypertens 2011 Mar 2
87 21270293 4F2hc stabilizes GLUT1 protein and increases glucose transport activity. Am J Physiol Cell Physiol 2011 May 6
88 21318884 Polyamine transport systems in mammalian cells and tissues. Methods Mol Biol 2011 1
89 21369940 Regulation of xCT expression and system x (c) (-) function in neuronal cells. Amino Acids 2012 Jan 1
90 21750865 Expression of 4F2hc (CD98) in pulmonary neuroendocrine tumors. Oncol Rep 2011 Oct 2
91 22216172 Functional induction of the cystine-glutamate exchanger system Xc(-) activity in SH-SY5Y cells by unconjugated bilirubin. PLoS One 2011 3
92 22373026 Relation of LAT1/4F2hc expression with pathological grade, proliferation and angiogenesis in human gliomas. BMC Clin Pathol 2012 Feb 28 1
93 22702504 High expression of CD98 alters epithelial barrier functions to promote induction of airway allergy. Clin Exp Allergy 2012 Jul 3
94 22898570 Cellular signaling of amino acids towards mTORC1 activation in impaired human leucine catabolism. J Nutr Biochem 2013 May 1
95 23085088 Expression of human heteromeric amino acid transporters in the yeast Pichia pastoris. Protein Expr Purif 2013 Jan 1
96 23297381 Intestinal epithelial CD98 directly modulates the innate host response to enteric bacterial pathogens. Infect Immun 2013 Mar 1
97 23441163 Lectins offer new perspectives in the development of macrophage-targeted therapies for COPD/emphysema. PLoS One 2013 2
98 24138531 Cytochrome P450-dependent catabolism of vitamin K: ω-hydroxylation catalyzed by human CYP4F2 and CYP4F11. Biochemistry 2013 Nov 19 1
99 24178689 The molecular basis of cystinuria: the role of the rBAT gene. Amino Acids 1996 Jun 1
100 24284901 Hook1, microtubules, and Rab22: mediators of selective sorting of clathrin-independent endocytic cargo proteins on endosomes. Bioarchitecture 2013 Sep-Dec 1