Title : Cellular signaling of amino acids towards mTORC1 activation in impaired human leucine catabolism.

Pub. Date : 2013 May

PMID : 22898570






1 Functional Relationships(s)
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1 The leucine/glutamine antiporter SLC7A5/SLC3A2 and the amino acid sensor MAP4K3 were identified as crucial determinants of signaling leucine availability to downstream targets. Leucine solute carrier family 3 member 2 Homo sapiens