Title : Functional induction of the cystine-glutamate exchanger system Xc(-) activity in SH-SY5Y cells by unconjugated bilirubin.

Pub. Date : 2011

PMID : 22216172






3 Functional Relationships(s)
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1 We have previously reported that exposure of SH-SY5Y neuroblastoma cells to unconjugated bilirubin (UCB) resulted in a marked up-regulation of the mRNA encoding for the Na(+)-independent cystine:glutamate exchanger System X(c)(-) (SLC7A11 and SLC3A2 genes). Bilirubin solute carrier family 3 member 2 Homo sapiens
2 We have previously reported that exposure of SH-SY5Y neuroblastoma cells to unconjugated bilirubin (UCB) resulted in a marked up-regulation of the mRNA encoding for the Na(+)-independent cystine:glutamate exchanger System X(c)(-) (SLC7A11 and SLC3A2 genes). Cystine solute carrier family 3 member 2 Homo sapiens
3 We have previously reported that exposure of SH-SY5Y neuroblastoma cells to unconjugated bilirubin (UCB) resulted in a marked up-regulation of the mRNA encoding for the Na(+)-independent cystine:glutamate exchanger System X(c)(-) (SLC7A11 and SLC3A2 genes). Glutamic Acid solute carrier family 3 member 2 Homo sapiens