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12 | 12091553 | ATP-inhibition of M current in frog sympathetic neurons involves phospholipase C but not Ins P(3), Ca(2+), PKC, or Ras. | J Neurophysiol | 2002 Jul |
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13 | 12414987 | Move over protein kinase C, you've got company: alternative cellular effectors of diacylglycerol and phorbol esters. | J Cell Sci | 2002 Dec 1 |
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14 | 12730099 | Integration of DAG signaling systems mediated by PKC-dependent phosphorylation of RasGRP3. | Blood | 2003 Aug 15 |
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16 | 14702343 | Rap1-mediated lymphocyte function-associated antigen-1 activation by the T cell antigen receptor is dependent on phospholipase C-gamma1. | J Biol Chem | 2004 Mar 19 |
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17 | 15064353 | Diacylglycerol-dependent binding recruits PKCtheta and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes. | Mol Biol Cell | 2004 Jun |
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18 | 15213298 | PKCdelta associates with and is involved in the phosphorylation of RasGRP3 in response to phorbol esters. | Mol Pharmacol | 2004 Jul |
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20 | 15657177 | Phosphorylation of RasGRP3 on threonine 133 provides a mechanistic link between PKC and Ras signaling systems in B cells. | Blood | 2005 May 1 |
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21 | 15899849 | A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells. | Mol Cell Biol | 2005 Jun |
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26 | 17486117 | The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospholipase D2. | Nat Cell Biol | 2007 Jun |
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28 | 17567957 | Regulation of RasGRP1 by B cell antigen receptor requires cooperativity between three domains controlling translocation to the plasma membrane. | Mol Biol Cell | 2007 Aug |
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29 | 17658605 | SKAP55 modulates T cell antigen receptor-induced activation of the Ras-Erk-AP1 pathway by binding RasGRP1. | Mol Immunol | 2008 Jan |
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30 | 17702895 | Essential role for Rap1 GTPase and its guanine exchange factor CalDAG-GEFI in LFA-1 but not VLA-4 integrin mediated human T-cell adhesion. | Blood | 2007 Nov 15 |
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32 | 18042941 | New insights into the mechanisms of SOS activation. | Sci STKE | 2007 Nov 27 |
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33 | 18077438 | Phorbol ester stimulation of RasGRP1 regulates the sodium-chloride cotransporter by a PKC-independent pathway. | Proc Natl Acad Sci U S A | 2007 Dec 11 |
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34 | 18160667 | A 2-gene classifier for predicting response to the farnesyltransferase inhibitor tipifarnib in acute myeloid leukemia. | Blood | 2008 Mar 1 |
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37 | 19100522 | A proapoptotic signaling pathway involving RasGRP, Erk, and Bim in B cells. | Exp Hematol | 2009 Jan |
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38 | 19168098 | Membrane localization of RasGRP1 is controlled by an EF-hand, and by the GEF domain. | Biochim Biophys Acta | 2009 Mar |
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39 | 19628710 | CalDAG-GEFI is at the nexus of calcium-dependent platelet activation. | Blood | 2009 Sep 17 |
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40 | 19896467 | Functional links between diacylglycerol and phosphatidylinositol signaling systems in human leukocyte-derived cell lines. | Biochem Biophys Res Commun | 2009 Dec 25 |
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41 | 19933860 | RasGRP1 is required for human NK cell function. | J Immunol | 2009 Dec 15 |
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42 | 20392800 | RasGRP1 stimulation enhances ubiquitination and endocytosis of the sodium-chloride cotransporter. | Am J Physiol Renal Physiol | 2010 Aug |
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43 | 20413728 | Integrin-independent role of CalDAG-GEFI in neutrophil chemotaxis. | J Leukoc Biol | 2010 Aug |
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44 | 21083522 | Farnesyltransferase inhibitors: where are we now? | Expert Opin Investig Drugs | 2010 Dec |
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45 | 21138839 | Decreased diacylglycerol metabolism enhances ERK activation and augments CD8+ T cell functional responses. | J Biol Chem | 2011 Feb 18 |
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46 | 21285350 | Phosphoinositide 3-kinase regulates plasma membrane targeting of the Ras-specific exchange factor RasGRP1. | J Biol Chem | 2011 Apr 8 |
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47 | 21673341 | Cytotoxicity of farnesyltransferase inhibitors in lymphoid cells mediated by MAPK pathway inhibition and Bim up-regulation. | Blood | 2011 Nov 3 |
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48 | 21775687 | Tight regulation of diacylglycerol-mediated signaling is critical for proper invariant NKT cell development. | J Immunol | 2011 Sep 1 |
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49 | 21856938 | G alpha i2 and ZAP-70 mediate RasGRP1 membrane localization and activation of SDF-1-induced T cell functions. | J Immunol | 2011 Sep 15 |
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50 | 21966541 | Basal LAT-diacylglycerol-RasGRP1 signals in T cells maintain TCRα gene expression. | PLoS One | 2011 |
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