Title : Move over protein kinase C, you've got company: alternative cellular effectors of diacylglycerol and phorbol esters.

Pub. Date : 2002 Dec 1

PMID : 12414987






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 RasGRP1 (in Ras/Raf/MEK/ERK signalling) and Munc13-1 (in neurotransmitter secretion) are examples of non-PKC diacylglycerol/phorbol-ester receptors that mediate diacylglycerol and phorbol-ester effects originally thought to be caused by PKC isozymes. Diglycerides RAS guanyl releasing protein 1 Homo sapiens
2 RasGRP1 (in Ras/Raf/MEK/ERK signalling) and Munc13-1 (in neurotransmitter secretion) are examples of non-PKC diacylglycerol/phorbol-ester receptors that mediate diacylglycerol and phorbol-ester effects originally thought to be caused by PKC isozymes. Diglycerides RAS guanyl releasing protein 1 Homo sapiens
3 RasGRP1 (in Ras/Raf/MEK/ERK signalling) and Munc13-1 (in neurotransmitter secretion) are examples of non-PKC diacylglycerol/phorbol-ester receptors that mediate diacylglycerol and phorbol-ester effects originally thought to be caused by PKC isozymes. Phorbol Esters RAS guanyl releasing protein 1 Homo sapiens
4 The examples of RasGRP1 and Munc13-1 show that detailed genetic analyses of C(1)-domain-containing non-PKC diacylglycerol/phorbol-ester receptors in mammals are ideally suited to achieve this goal. Diglycerides RAS guanyl releasing protein 1 Homo sapiens